T lymphocyte


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Related to T lymphocyte: B lymphocyte, Cytotoxic T lymphocyte

T lym·pho·cyte

a lymphocyte formed in the bone marrow from which it migrates to the thymic cortex to become an immunologically competent cell; T lymphocytes have long lifespans (months to years) and are responsible for cell-mediated immunity; T lymphocytes form rosettes with sheep erythrocytes and differentiate and divide in the presence of transforming agents (mitogens); T lymphocytes have characteristic T cell receptor-CD3 complexes as surface markers and may be further categorized by function, such as helper and cytotoxic.
See also: B lymphocyte.
Synonym(s): T cell

T lymphocyte

n.
See T cell.

T lym·pho·cyte

(lim'fŏ-sīt)
A thymocyte-derived lymphocyte of immunologic importance that is responsible for cell-mediated immunity. These cells have the characteristic T3 surface marker and may be further divided into subsets according to function, such as helper, suppressor, and cytotoxic.
See also: B lymphocyte
Synonym(s): T cell.

T lym·pho·cyte

(lim'fŏ-sīt)
Lymphocyte formed in bone marrow from which it migrates to thymic cortex to become an immunologically competent cell.

Patient discussion about T lymphocyte

Q. What is the best treatment for Acute Lymphocytic Leukemia? What is the best treatment for Acute Lymphocytic Leukemia? Can you please give me the hospital names and the location where the treatment could be done?

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References in periodicals archive ?
For a long time, the CD4+ T lymphocytes have been considered the only regulatory cells, due to their ability to secrete cytokines that regulate various processes of the immune response.
IL-2 plays a key role in the activation, survival, expansion, and function of T lymphocytes. It also appears to be crucial in the maintenance of regulatory T cell- (Treg-) mediated immunotolerance toward self-antigens, supported by the fact that IL-2-deficient mice develop severe autoimmunity with very low Treg and very high effector T numbers [7-9].
(15.) Los M, Droge W, Stricker K, Baeuerle PA, Schulze-Osthoff K: Hydrogen peroxide as a potent activator of T lymphocyte functions.
This was proven in vitro when differentiating naive [CD8.sup.+] T lymphocyte with TGF-[beta] and IL-2 and obtaining lymphocytes with suppressor action expressing [CD127.sup.-][CD25.sup.hi][FoxP3.sup.hi] markers [86]; however, these lymphocytes are not so helpful.
Furthermore, hyperglycemia and ketoacidosis were found to increase the levels of proinflammatory cytokines and the numbers of activated T lymphocytes in diabetic patients [14].
At 3 days postinfection, neither DEP exposure nor Listeria infection resulted in significant changes in T lymphocytes when compared with the air-exposed, noninfected control (data not shown).
Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children.
Rotavirus-specific cytotoxic T lymphocytes passively protect against gastroenteritis in suckling mice.
Next, the researchers turned to the peripheral blood mononuclear cells, a hodgepodge of white cells, including CD4 T lymphocytes, in the bloodstream.
Yeo, PhD, assistant professor in the Department of Cellular and Molecular Medicine and Institute for Genomic Medicine, said that researchers have been trying for a very long time to understand when and how T lymphocytes give rise to effector and memory cells during an infection.
Giorgi, Quantitation of CD38 Activation Antigen Expression on [CD8.sup.+] T Cells in HIV-1 Infection Using CD4 Expression on [CD4.sup.+] T Lymphocytes as a Biological Calibrator, Cytometry 33, 123-132 (1998).