T lymphocyte

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Related to T lymphocyte: B lymphocyte, Cytotoxic T lymphocyte

T lym·pho·cyte

a lymphocyte formed in the bone marrow from which it migrates to the thymic cortex to become an immunologically competent cell; T lymphocytes have long lifespans (months to years) and are responsible for cell-mediated immunity; T lymphocytes form rosettes with sheep erythrocytes and differentiate and divide in the presence of transforming agents (mitogens); T lymphocytes have characteristic T cell receptor-CD3 complexes as surface markers and may be further categorized by function, such as helper and cytotoxic.
See also: B lymphocyte.

Synonym(s): T cell

T lymphocyte

See T cell.

T lymphocyte

See lymphocyte, T cell.

T lym·pho·cyte

(lim'fŏ-sīt)

A thymocyte-derived lymphocyte of immunologic importance that is responsible for cell-mediated immunity. These cells have the characteristic T3 surface marker and may be further divided into subsets according to function, such as helper, suppressor, and cytotoxic.
See also: B lymphocyte
Synonym(s): T cell.

T lym·pho·cyte

(lim'fŏ-sīt)

Lymphocyte formed in bone marrow from which it migrates to thymic cortex to become an immunologically competent cell.

T lymphocyte

see T lymphocyte.

Patient discussion about T lymphocyte

Q. What is the best treatment for Acute Lymphocytic Leukemia? What is the best treatment for Acute Lymphocytic Leukemia? Can you please give me the hospital names and the location where the treatment could be done?

A. Combination chemotherapy. St. Jude Children's Research Hospital has reported a 5-year-survival rate of more than 90 percent for acute lymphoblastic leukemia (ALL)- on adults it's a bit lower but still a remarkable success. About the hospital- it depends where you do you live I guess…

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References in periodicals archive ?

B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes.

Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). II. Effects of DEPs on T-cell-mediated immune responses in rats. (Research)

A thymic deficiency in the newborn will result in lack of T lymphocytes and in the quick appearance of physiological complications that will translate into slowed growth rate or repetitive infections, and possibly lead to premature death.

Thymus: Master Gland of Immunity

Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children.

Flow cytometry and T-cell response monitoring after smallpox vaccination

Rotavirus-specific cytotoxic T lymphocytes passively protect against gastroenteritis in suckling mice.

HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women.

Vaccines for mucosal immunity to combat emerging infectious diseases

Previous research has shown that killer T lymphocytes produced in the lab using conventional methods are inefficient in killing cancer cells mainly because they have a very short life-span, which limits their use as treatment for cancer.

To overcome these problems, the Japanese researchers led by Hiroshi Kawamoto reprogrammed mature human killer T lymphocytes into iPS cells and investigated how these cells differentiate.

The team induced killer T lymphocytes specific for a certain type of skin cancer to reprogram into iPS cells by exposing the lymphocytes to the 'Yamanaka factors'.

The iPS cells obtained were then grown in the lab and induced to differentiate into killer T lymphocytes again.

Cancer-killing technology from induced stem cells created

Without a full roster of healthy T lymphocytes, the immune system will also lose the battle against microbes such as Pneumocystis carinii.

In Weiner's research, the vpr protein protected T lymphocytes that had been designed in the laboratory to resemble HIV-infected T lymphocytes.

For example, T lymphocytes treated with the vpr protein and RU486 continued to proliferate and to secrete immune-boosting cytokines.