Trypanosoma cruzi

(redirected from T cruzi)

Try·pan·o·so·ma cru·zi

a species that causes South American trypanosomiasis and is endemic in Mexico and various countries of Central and South America; transmission and infection are common only where the triatomine bug vector defecates while taking blood, because the bug's feces contain the infective agents that are scratched into the skin or brought in contact with mucosal surfaces. Trypomastigotes are found in the blood, and amastigotes occur intracellularly in clusters or colonies in the tissues; heart muscle fibers and cells of many other organs are attacked, the organisms not being restricted to macrophages as in visceral leishmaniasis; humans, dogs, cats, house rats, armadillos, bats, certain monkeys, and opossums are the usual vertebrate hosts; vectors are members of the family Triatominae. Also known as Schizotrypanum cruzi, a distinct generic designation widely used in the endemic regions.

Try·pan·o·so·ma cru·zi

(trī-pan'ō-sō'mă krūz'ī)
A species of protozoan flagellates that causes South American trypanosomiasis; transmission and infection are common only where the triatomine bug vector defecates while taking blood, because the bug feces contain the infective agents that are scratched into the skin or brought in contact with mucosal surfaces. Trypomastigotes are found in the blood; heart muscle and other organs are attacked.

Trypanosoma cruzi

The causative agent of American trypanosomiasis (Chagas disease). It is transmitted by triatomids (bloodsucking insects of the family Reduviidae).
See also: Trypanosoma
References in periodicals archive ?
The T cruzi is sometimes called the "silent killer" because many people who get infected by the parasite don't show any symptoms right away, even though acute Chagas disease occurs immediately after infection.
B-C) Phylogenetic position of T cruzi responsible for the 2017 Chagas disease outbreak in the Brazilian Amazon, based on the cytocrome oxidase subunit II gene sequences (bestfit model: Hasegawa-Kishino-Yano) and on the GPI gene sequences (best-fit model: Kimura 2-parameter).
La presencia de T cruzi en mamiferos y vectores del valle de Caracas [34], motivo a los autores a profundizar esta situacion estableciendo los parametros que caracterizan a la enfermedad de Chagas como una zoonosis urbana emergente [46].
The results of this study evidence the transmission cycle that occurs between the hosts/reservoirs (rodents), the vector (T dimidiata), and the pathogen (T cruzi) at the study site.
Se realizo un estudio de tipo observacional, descriptivo, retrospectivo, cuya poblacion comprendio todos los donantes de sangre del Departamento de Caqueta, reactivos y confirmados para T cruzi por serologia, entre 1995 y 2010; asi mismo, se realizo busqueda de registros de posibles casos canalizados por una via diferente a la de banco de sangre, en el Laboratorio de Salud Publica Departamental.
Testing for T cruzi antibodies was pursued due to prior residence in an endemic area and cardiac history, and results were positive.
In October 2016, an 18-year-old US Air Force trainee screened positive for T cruzi infection when he donated blood at Joint Base San Antonio (JBSA), Texas.
La Reaccion en Cadena de la Polimerasa (PCR), mediante el empleo de los primers S35-S36, ha permitido la deteccion de T cruzi en tejidos infectados con cepas I y II del parasito y ha sido utilizada para monitorear pacientes con cardiomiopatia chagasica.
Sin embargo, el ensayo de PCR anidada (PCR-A) (10), el ensayo de PCR cuantitativa en tiempo real (PCR-RTQ) (11), y el ensayo de oligocromatografia (OligoC) (12) se han realizado para mejorar la deteccion de ADN de T cruzi. Dada la heterogeneidad de los resultados reportados de las pruebas disponibles para el diagnostico, el objetivo de este estudio fue comparar la precision de los metodos serologicos y moleculares para detectar la infeccion por T.
Accordingly, mice that are genetically deficient in Toll-like receptors (TLRs) and their adaptors (MyD88 and TRIF), the NOD-like receptors (NLR), or inflammasome activators are more susceptible to experimental T cruzi infection [5, 23, 24].