systemic therapy

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systemic therapy

Therapeutics Any therapy that reaches target tissues via the systemic circulation


pertaining to or affecting the body as a whole.

systemic inflammatory response (SIR)
a specific condition recognized in critical care medicine, characterized by febrile response, increased heart and respiratory rates, and leukocytosis.
systemic lupus erythematosus
systemic neuroaxial dystrophy
systemic therapy
treatment with a drug that is absorbed into the bloodstream and distributed to all parts of the body except where there is a specific barrier.
References in periodicals archive ?
Looking at therapy sequence in those who had the same type of systemic therapy, but with chemotherapy before or after surgery, you see a suggestion that giving systemic therapy first with a clinical response, which is a favorable prognostic indication, leads to a selection bias in choosing patients for surgery.
Currently, all biologic treatments for psoriasis, including anti-tumor necrosis factor therapies (anti-TNFs) and Stelara (ustekinumab) are recommended for second-line systemic therapy in Europe.
Taken together, findings from these [and other] investigators provide strong evidence that patients undergoing partial mastectomy, whole-breast irradiation, and systemic therapy for early breast cancer with microscopic sentinel lymph node metastasis can be treated effectively and safely without axillary node dissection," they said.
STELARA is approved in Canada for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for phototherapy or systemic therapy.
The management of patients with renal cancer having localized or advanced disease is detailed, and surgical approaches for primary and metastatic tumors, symptom palliation, and systemic therapy for metastatic disease are discussed.
She presented a prospective single-center study that indicated axillary radiation plus systemic therapy provided adequate local control in such patients--and with a substantial reduction in morbidity, compared with axillary dissection.
In addition, our 2 patients were initially treated with systemic therapy rather than local therapy, and both have been in remission for more than 2 years.
Food and Drug Administration for the treatment of cutaneous T-cell lymphoma in patients who have received at least one prior systemic therapy.
Novartis announced today that the Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending approval of Cosentyx(TM) (secukinumab, formerly known as AIN457) as a first-line systemic treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy.
This edition has been updated and expanded with new chapters on radiation therapy and the role of nurse navigation, as well as more detailed information on surgical approaches, systemic therapy, and complementary approaches.
Pediatric cancers are often microscopically disseminated--rather than localized--at the time of diagnosis, so systemic therapy is almost always required.
EXPRESS was a Phase 3, multi-center, randomized, double-blind, placebo-controlled trial that evaluated the safety and efficacy of REMICADE induction and maintenance therapy in 378 adult patients with chronic, stable plaque psoriasis involving at least 10 percent body surface area (BSA), a minimum PASI score of 12 and who were candidates for phototherapy or systemic therapy.