transfusion guidelines

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transfusion guidelines

Transfusion medicine Guidlelines for use of blood components, which are usually written in a hospital's policy manual. See Transfusion criteria, Transfusion medicine.
Transfusion guidelines, general criteria
Hemoglobin
 < 8g/dL if healthy and stable
 < 11g/dL if Pt is at risk of ischemia
Acute blood loss ≥ 15% (est) blood volume, tachycardia, oliguria
Symptomatic anemia resulting in tachycardia, change in mental status, cardiac ischemia, or SOB Transfusion 1996; 36:144. See Transfusion guidelines.
Packed RBCs  
•  Hemorrhage
•  Active Physiologic instability, including tachycardia, ↓ in systolic BP > 30 mm Hg below baseline, orthostatic hypotension, angina, mental confusion, agitation
•  Chronic Physiologic instability–see above, refractory state.
•  Sickle cell anemia
Refractory crisis, acute lung syndrome, CVA, priapism, hepatic infarct, acute papillary necrosis, general anesthesia, contrast studies
Platelets  
• Platelet count < 30,000/µL
•  Functional platelet deficit
•  Surgical prophylaxis
•  Massive bleeding
Cryoprecipitate  
•  Active bleeding, fibrinogen < 100 mg/dL
•  Massive bleeding
•  DIC w/ bleeding
•  10 fibrinolysis
Dysfibrinogenemia
Majorin fibrinogen, factor VIII, von Willebrand factor
± in reversible liver disease
Queens Hospital Medical Center, 1990
References in periodicals archive ?
Mircera is an erythropoietin receptor activator indicated for the treatment of symptomatic anemia in chronic kidney disease, which received FDA approval in November 2007.
Packed red blood cell transfusions maybe needed for patients with severe symptomatic anemia (e.
Retacrit is used to treat symptomatic anemia associated with chronic renal failure in adult and pediatric patients and anemia in adult patients receiving chemotherapy for solid tumors, malignant lymphoma or multiple myeloma.
34) Cases with an IgM paraprotein of more than 3 g/dL and/or more than 10% marrow infiltration, but still without constitutional symptoms, symptomatic anemia, and hyperviscosity have been classified as smoldering WM.
A 50-year-old African American woman with iron deficiency anemia secondary to menorrhagia and uterine fibroids was admitted for symptomatic anemia, requiring blood transfusions.
A 59-year-old female was admitted for symptomatic anemia after presenting to the emergency room with progressively worsening shortness of breath that had developed in the preceding 4 weeks.
Jude hematologists reported on six previously healthy adolescents treated for acute, symptomatic anemia.
Patients with symptomatic anemia, postural hypotension, or lightheadedness should avoid prolonged standing poses and move slowly when transitioning between positions.
A 52-year-old woman was transferred from a rehabilitation facility for symptomatic anemia.
The patient was taken for exploratory laparotomy due to symptomatic anemia.
Based on the acceptance of a Marketing Authorization Application (MAA) submitted by Takeda, peginesatide is currently under review by the European Medicines Agency (EMA) for the treatment of symptomatic anemia associated with chronic kidney disease in adult patients on dialysis.
The patient was admitted to the hospital, where she received multiple transfusions for symptomatic anemia and eventually underwent gastric antrectomy to control the hemorrhage.

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