Brenner, Sydney

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Brenner, Sydney

(1927-) South African scientist (1927-) who discovered the principles of how DNA instructs cells to make proteins. In 1960s he established the existence of MESSENGER RNA for TRANSLATION into proteins and showed that the nucleotide sequence of mRNA determines the order of AMINO ACIDS in proteins. Together with Francis CRICK, he proposed that an amino acid is coded by a triplet code (see CODON of RNA. Brenner was the first to sequence the genome of an entire multicellular organism, the worm Caenorhabditis elegans, which provided the basis for sequencing the human genome (see HUMAN GENOME PROJECT). In 2002 he was awarded the Nobel Prize for Medicine, with J.E. Sulston and H.R. Horvitz, for contributions to understanding how genes regulate organ growth and the process of PROGRAMMED CELL DEATH.

Brenner,

Sydney, South African-born English scientist, 1927–, joint winner of 2002 Nobel Prize for work related to genetic regulation of organ development and cell death.
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Sydney Brenner, the 2002 Nobel Prize winner for Physiology or Medicine, and Professor Jeffrey H.
Founded in 1996 by Nobel-prize winner Sydney Brenner, MSI is an independent, not-for-profit research institute.
elegans has been the subject of intense scrutiny since the work begun by Sydney Brenner in the 1960s and culminating with his lab's 2002 Nobel in Medicine for Physiology.
James Watson was first in a series of other eminent scientists that interacted with Crick as a foil, and others included Sydney Brenner and Christof Koch.
The worm was the first multicellular organism to have its genetic code mapped, and this finding secured a Nobel prize for the trio of John Sulston, Bob Horvitz, and Sydney Brenner.
Sir John Sulston, Dr Sydney Brenner and US scientist Robert Horvitz were given the honour for their work in genetics.
Britons Sydney Brenner, 75, Sir John Sulston, 60, and American Robert Horvitz, 55, shared the prize, worth pounds 650,000.
The Molecular Sciences Institute (MSI) was founded by Nobel-prize winner Sydney Brenner as an independent, nonprofit research institute.
The honored trio is Sydney Brenner of the Molecular Sciences Institute in Berkeley, Calif.
Sydney Brenner, Population Genetics Technologies creates products that accelerate large-scale population studies, through the simultaneous analysis of multiple individual genomes.
With the election of Joanne Chory and non-resident fellow Carla Shatz, the Salk Institute's current roster of Royal Society members includes Francis Crick, Renato Dulbecco, Sydney Brenner, Tony Hunter, and non-resident fellows Elizabeth H.
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