Brenner, Sydney

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Brenner, Sydney

(1927-) South African scientist (1927-) who discovered the principles of how DNA instructs cells to make proteins. In 1960s he established the existence of MESSENGER RNA for TRANSLATION into proteins and showed that the nucleotide sequence of mRNA determines the order of AMINO ACIDS in proteins. Together with Francis CRICK, he proposed that an amino acid is coded by a triplet code (see CODON of RNA. Brenner was the first to sequence the genome of an entire multicellular organism, the worm Caenorhabditis elegans, which provided the basis for sequencing the human genome (see HUMAN GENOME PROJECT). In 2002 he was awarded the Nobel Prize for Medicine, with J.E. Sulston and H.R. Horvitz, for contributions to understanding how genes regulate organ growth and the process of PROGRAMMED CELL DEATH.

Brenner,

Sydney, South African-born English scientist, 1927–, joint winner of 2002 Nobel Prize for work related to genetic regulation of organ development and cell death.
References in periodicals archive ?
NUS President Prof Tan said, My heartiest congratulations to Dr Sydney Brenner on receiving the Singapore National Academy of Science Honorary Fellowship, and to Nanyang Technological University President Bertil Andersson, Institute of Bioengineering and Nanotechnology Executive Director Jackie Ying, my NUS colleagues Ding Jeak Ling, Lai Choy Heng, Lee Hian Kee and Ooi Beng Chin on becoming Academy Fellows.
elegans, the famous worm subject of many studies on embryonic development and developmental genetic, even though Sydney Brenner, who pioneered using the worm as a model organism, is briefly mentioned.
Cuando la asamblea Nobel del Instituto Karolinska otorgo el Premio Nobel de Medicina a Sydney Brenner, H.
Nobel Prize winner Dr Sydney Brenner, who devised the method for obtaining sequence information from thousands of genomes simultaneously, said scientists did not need to know everything about every gene in order to combat disease.
He shares the Nobel Prize with ex-colleague Dr Sydney Brenner and American scientist Robert Horvitz.
Sir John Sulston, former director of the Wellcome Trust Sanger Centre at Hinxton, Cambridgshire, shares the honour with excolleague Dr Sydney Brenner, now based in the United States.
The scientists are Sydney Brenner of the Molecular Sciences Institute in Berkeley, Calif.
Sydney Brenner, the 2002 Nobel Prize winner for Physiology or Medicine, and Professor Jeffrey H.
In fact, four of our science Nobel prize winners - Max Theiler, Alan Cormack, Aaron Klug and Sydney Brenner - followed this path.
elegans has been the subject of intense scrutiny since the work begun by Sydney Brenner in the 1960s and culminating with his lab's 2002 Nobel in Medicine for Physiology.
James Watson was first in a series of other eminent scientists that interacted with Crick as a foil, and others included Sydney Brenner and Christof Koch.
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