Curative surgery for bronchogenic carcinoma was not considered as excision biopsy from right supraclavicular lymph node
showed metastatic deposit (T1bN3M0, stage Nib).
A biopsy of a left supraclavicular lymph node
identified a metastatic papillary adenocarcinoma without atypia; some rare follicular structures were filled with eosinophilic material that mimicked a colloid (figure 2).
Biopsies from an enlarged supraclavicular lymph node
revealed metastatic testicular teratocarcinoma.
A biopsy of her supraclavicular lymph node
confirmed the diagnosis of a high-grade carcinoma, which was hormone receptor and Her2/neu-negative like her previous cancer and shared the same histologic morphology.
Supraclavicular lymph node
irradiation is indicated when 4 or more axillary nodes are invaded, usually suggesting a 15-20% risk of supraclavicular lymph node
Biopsy is also indicated if there is a supraclavicular lymph node
or concomitant constitutional symptoms (weight loss or night sweat)(2) (SOR: B, case series).
1) Hodgkin disease characteristically presents as asymptomatic supraclavicular lymph node
enlargement in a young adult, but may also be discovered in the mid or high neck or in the axilla.
M1: Distant metastasis (including metastasis to ipsilateral supraclavicular lymph node
Neck examination revealed enlarged level IV and supraclavicular lymph node
on left side approx.
Australian Cancer Network Diagnosis and Management of Lymphoma Guidelines, approved by the National Health and Medical Research Council (NHMRC), identified the following factors useful in determining the need for a lymph node biopsy: (88) age more than 40 years; supraclavicular lymph node
location; nodal diameter greater than 2.
A fine needle biopsy of the left supraclavicular lymph node
Cervical non-supraclavicular lymph node
involvement was seen in 3 patients, and supraclavicular lymph nodes
in 4; pulmonary metastases occurred in 7, and liver metastases in 1 patient.