Super Coiled DNA

Double-stranded circular DNA in which either overwinding or underwinding of the duplex makes the circle twist; the conformation of a covalently closed-circular DNA molecule, which is coiled by torsional strain into the shape taken by a wound up elastic band
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The results shows in the DNA nicking assay describes clearly there is no significant harm in the DNA even in higher concentration (80 ng) the super coiled DNA does not get much affected by the peptide shown in figure 1 further the reports characterizes the experimental system and presents evidence that DNA strand interruptions indicated by binding to circular DNA from the same preparation was significantly high (lanes 3-4), indicating that binding to linear DNA may be due to non-specific aggregation shown in figure 3.