Cotrimoxazole suspensions contain the APIs trimethoprim (TMP) and sulphamethoxazole
(SMZ) with specifications of 92.5-107.5% for the two drugs.
There exist strong association amongst the prevalence of oxytetracycline resistance with streptomycin and sulphamethoxazole
/trimethoprim resistance in E.
Some of the drugs that were implicated in these ADRs were: chloroquine 12 (29.3%), sulphadoxine-pyrimethamine 7 (12.2%), artemether-lumefantrine 4 (9.8%), cotrimoxazole 3 (7.3%), tramadol 2 (4.9%), and sulphamethoxazole
The antibiotics used for this test were Amoxyclav, Cephalexin, Ciproflaxacin, Clindamycin, Cloxacillin, Co-Trimaxazole, Erythromycin, Tetracyclin, Ampicillin, Carbenicilllin, Cephatoxamine, Chloramphenicol, Co-Trimazine, Gentamicin, Norflaxacin, Oxacillin, Amikacin, Bacitracin, Novobiocin, Vancomycin, Penicillin-G, Tobramycin, Cephaloridine, Kanamycin, Linomycin, Methicillin, Oleandomycin, Nalidixic acid, Sulphamethoxazole
, Cefactor, Cefixime, Piperacillin and Cefoperazone.
Susceptibilities of the following antibiotics were tested; Amoxicillin/Clavulanic acid (Augmentin), Fusidic acid, Penicillin, Methicillin/Oxacillin, Gentamicin and Trimethoprim/ Sulphamethoxazole
at 20, 10, 10, 5/1, 10 and 1.25/23.75 Hgms concentration respectively for Staphylococcus species.
mallei activity of sulphonamides (sulphamonomethoxine, sulphasalazine, sulphanilamide and sulphamethoxazole
) in combination with trimethoprim (TMP).
Cotrimoxazole, a combination of sulphamethoxazole
and trimethoprim is a broad spectrum antibacterial agent with proven efficacy in the treatment of Plasmodium falciparum malaria (6-8).
The study carried out in two hospitals -- Ujjain Charitable Trust Hospital in Ujjain and Chandrikaben Rashmikant Gardi Hospital at Surasa -- in Madhya Pradesh found water discharged as effluent carried many types of commonly used antibiotics such as ciprofloxacin, metronidazole, norfloxacin, sulphamethoxazole
, ceftriaxone, ofloxacin, levofloxacin and tinidazole.
In vitro cytotoxicity as a marker of hypersensitivity to sulphamethoxazole
in patients with HIV.
It was observed resistance of Lactobacillus strains to a mixture of 1.25 [micro]g of trimethoprim and 23.75 [micro]g of sulphamethoxazole
. However they were sensitive to 10 [micro]g of ampiciline.
In Saudi Arabia, Escherichia coli isolated from chicken intestines were found to be resistant to many antibiotics such as ampicillin, chloramphenicol, gentamycin, tetracycline, trimethoprim and sulphamethoxazole
(Al-Ghamdi et al.., 1999).
These plates contained different antimicrobial agents (concentrations in [mu]/ml ampicillin (32), cefuroxime (16), ceftazidime (16), nalidixic acid (32), trimethoprim (8), sulphamethoxazole
(512), tetracycline (4) and ciprofloxacin (1).