sulforaphane


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sulphoraphane

An isothiocyanate phytochemical present—after conversion from glucoraphanin by myroinase—in cruciferous vegetables (e.g., Brussels sprouts, broccoli, cabbage), which has anticarcinogenic, antimicrobial and antidiabetic activity in experimental systems. 
It stimulates the production of phase-2 enzymes that play a role in detoxifying carcinogens; in rats, sulphoraphane reduces the incidence of mammary tumours induced by dimethylbenzanthracene (DMBA).

sulforaphane

Sulforaphane glucosinolate, sulphoraphane Oncology An isothiocyanate phytochemical or 'nutriceutical' in cruciferous vegetables–eg, broccoli, which may prevent CA. See Cruciferous vegetables, Nutriceutical.

sulforaphane

, sulphoraphane (sŭl-fŏr′ă-fān″) [″ + Gr. phainein, to show],

SF

A sulfur-containing compound found in vegetables of the mustard family (Cruciferae). Like other isothiocyanates, it has been shown to prevent cancer in animals.
References in periodicals archive ?
I made the connection that perhaps the sulforaphane in the sprouts was involved in the response and began investigating the action of sulforaphane against Helicobacter pylori.
Sulforaphane is derived from a glucosinolate precursor, glucoraphanin, by the activity of myrosinase.
The strange thing is that young shoots of broccoli, similar in appearance to cress, actually contain up to 100 times more concentrated sulforaphane than in the mature vegetable.
Other dietary factors, such as sulforaphane obtained from broccoli, can reduce oxidative stress and prevent or reverse metabolic deregulation.
While researching the anticancer benefits of sulforaphane in previous research, Emily Ho and her colleagues identified an enzyme in prostate cancer cells that is affected by exposure to the compound.
Sulforaphane inhibits growth of human breast cancer cells and augments the therapeutic index of the chemotherapeutic drug, gemcitabine.
The compound sulforaphane, found in the vegetable, slows the destruction of cartilage in joints linked with osteoarthritis, say scientists in research out today.
Sulforaphane, which is found at high levels particularly in broccoli, has been shown to destroy prostate tumours while leaving normal cells healthy.
Sulforaphane inhibits histone deacetylases, (HDACs), thereby interfering with the cellular triggers for cancer.
You can read more about sulforaphane in the September 2010 newsletter.
Additionally, these packets also contain phytonutrients such as sulforaphane and indoles (in cruciferous vegetables) and ellagic acid (in strawberries), which promote healthy cell function and development.
Brussels sprouts - as well as being a good source of vitamin C, B1 and folate, sprouts contain a phyto-nutrient called sulforaphane, which causes the liver to produce enzymes that help to detoxify us;