suicide substrate

(redirected from Suicide inhibitor)
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su·i·cide sub·strate

a competitive inhibitor that is converted to an irreversible inhibitor at the active site of the enzyme.
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The ODC suicide inhibitor [alpha]-DMFO has been used in studies of the roles of ODC and polyamines at the biochemical and physiological levels (Bitonti et al., 1985; Pegg, 1986).