Cause: Five strains of Ebola virus have been identified 6 Bundibugyo virus,
Sudan virus, Tai Forest virus, Zaire virus and Reston virus.
Sudan virus Trypanosoma brucei West Nile virus Yersinia pestis Yellow fever virus Zika virus * Applied Biosystems, Carlsbad, CA, USA.
Epitope data from the genus Ebolavirus extracted from the IEDB (as described above) were first oriented for position to reference GP sequences; data to date come from only EBOV,
Sudan virus, and Bundibugyo virus GPs and include isoforms GP and ssGP.
A separate contract (HHSO100201700023C) of $1.9 million has been awarded (with options for an additional $6.6 million) to support Mapp's preclinical stage products for
Sudan virus (MBP134) and pan-Marburg virus (MBP091).
Four of these are known to cause disease in humans, including Zaire Ebola virus,
Sudan virus, Tai Forest virus (isolated in Ivory Coast), and Bundibugyo virus.
These four viruses are Bundibugyo virus (BDBV), (Zaire) Ebola virus (EBOV),
Sudan virus (SUDV), and the Tai Forest virus (TAFV).
BDBV, Bundibugyo virus; EBOV, Ebola virus; ID, specimen identification number; MARV(Mus), Marburg virus-Musoke; MARV(Ang), Marburg virus-Angol a; RESTVm, Reston virus-monkey; RESTVp, Reston virus-pig; SUDV,
Sudan virus; RAVV, Ravn virus; TAFV, Tai Forest virus.
In 1976, the investigation of concurrent outbreaks of a hemorrhagic fever syndrome (Ebola virus disease [EVD]) in Zaire (currently Democratic Republic of Congo) and Sudan (currently Republic of South Sudan) (1,2) led to isolation of 2 viruses now referred to as Ebola virus (EBOV) and
Sudan virus, respectively, and to identification of a newly recognized viral hemorrhagic fever genus, Ebolavirus (family Filoviridae).
(5) proposed that the
Sudan virus was novel among Congo Basin isolates because of this large duplication of genetic information not seen in other monkeypox viruses sequenced to date.
To facilitate rapid differential diagnosis of VHF agents, we established the Greene MassTag Panel VHF version 1.0, which comprises the following targets: Ebola Zaire virus (ZEBOV), Ebola
Sudan virus (SEBOV), MARV, LASV, RVFV, CCHFV, Hantaan virus (HNTV), Seoul virus (SEOV), YFV, and KFDV.