This transcription factor with a heterodimeric structure comprised an oxygen-regulated a subunit
(HIF-[alpha]), and a constitutively expressed [beta] subunit
(Semenza 2000) is translocated to the nucleus during hypoxia, where it binds to specific DNA sequences to regulate a large number of genes implicated in energetic metabolism, including 6-phosphofructo-2-kinase, fructose-2,6-biphosphatase 3 and 4, and COX subunits
4-1 (Minchenko et al.
39,42) This observation provided an important conclusion that at least one of three [beta] subunits
Isolation of the alpha subunits
of GTP-binding regulatory proteins by affinity chromatography with immobilized beta gamma subunits
The two [alpha] and four [beta] integrin subunits
of Nematostella vectensis
, particularly [alpha]2 and [gamma]1 subunits
, and AD.
At Glu-B1 locus, 5 different HMW glutenin subunits
combinations (17+18, 13+16, 7+9, 7+8, 7) appeared in the Pakistani varieties.
Phylogenetic analysis indicated that the Bdor[alpha]6 was most closely related to D[alpha]6 and Agam[alpha]6 with these 3 subunits
clustering together, and also showed the relationships with different subunits
from other species.
V-ATPases have been found to be practically identical in terms of the composition of their subunits
in all eukaryotic cells.
Because these receptors are so similar in structure, it was assumed that they function in much the same way, but when we altered the dimer interface, the site where two subunits
come together within each pair, we found that the NMDA receptor works just the opposite of the way that the AMPA receptor works," points out Popescu.
400kDa) was observed which corresponds to two hemocyanin subunits
(named as Siphonaria subunit
S1 and S2).
R&D was usually conducted in the home country headquarters, and innovations were introduced to subunits
abroad, which, if they did any R&D at all, focused on tailoring technologies to the specific needs of the local market.
Then, they distribute comparative data to help every subunit
honestly appraise its own performance--to ensure that subunits
with similar targets have a realistic understanding of how their performance compares with that of their peers.