substantia innominata

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in·nom·i·nate sub·stance

the region of the forebrain that lies inferior to the anterior half or so of the lentiform nucleus, extending in the frontal plane from the lateral preopticohypothalamic zone laterally over the optic tract to the amygdala (amygdaloid body); rostrally it tapers off over the superior border of the olfactory tubercle, and caudally it ends where the internal capsule reaches the surface to form the cerebral peduncle or pes pedunculi. Notable among its polymorphic cell population is the large-celled basal nucleus of Meynert. These magnocellular elements within the innominate substantance are present in the medial septum and the diagonal band of Broca, but they occur in largest numbers ventral to the globus pallidus. Histochemical evidence indicates that magnocellular elements distribute cholinergic fibers widely in the cerebral cortex and that these cells undergo selective degeneration in Alzheimer disease.
Synonym(s): substantia innominata [TA]
Farlex Partner Medical Dictionary © Farlex 2012

substantia innominata

A region of the brain lying between the globus pallidus of the basal ganglia and the ventral surface of the forebrain.
See also: substantia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The neuropathology of PD, however, remained unknown, till Fritz Heinrich Lewy, (4) who studied the neuropathology of PD at Munich University, described eosinophilic intracytoplasmic inclusions in the dorsal vagal nuclei and substantia innominata of PD brains in 1912.

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