subacute combined degeneration

subacute combined degeneration

Subacute combined degeneration of the spinal cord Neurology A disorder caused by vitamin B12 deficiency, characterized by weakness, sensory defects, mental changes, vision defects, often associated with megaloblastic anemia Clinical SCD causes demyelination, affecting the spinal cord, brain, optic and peripheral nerves, with axonal destruction. See Vitamin B12 deficiency.
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She says the nitrous oxide (NOS) inside has left her with no feeling in most of her body after she contracted Lichtheim's disease, also known as subacute combined degeneration of the spinal cord.
Given the medical history and examination results, according to the diagnosis standard of ICD-10, the patient was diagnosed with psychoactive substances (nitrous oxide) dependence syndrome; psychotic disorders secondary to psychoactive substances (nitrous oxide); and subacute combined degeneration of spinal cord.
[5] Nonstandard abbreviations: MMA, methylmalonic acid; ALT, alanine transaminase; AST, aspartate transaminase; RDW, red cell distribution width; HCT, hematocrit; EMG, electromyography; Cbl, cobalamin; Met, methionine; Hcy, homocysteine; AdoCbl, adenosylcobalamin; MeCbl, methylcobalamin; tHcy, total Hcy; 2MCA, 2-methylcitric acid; SCD, subacute combined degeneration of spinal cord; PA, pernicious anemia; [N.sub.2]O, nitrous oxide; GDS, Global Drug Survey; SAM, 5- adenosykmethionine; Hb, hemoglobin.
Subacute combined degeneration (SCD) is one of the neurological sequels to vitamin B12 deficiency.
Subacute combined degeneration (SCD) is a rare neurological complication of vitamin B12 deficiency, characterized by the demyelination of dorsal and lateral spinal cord.
Frequent neurologic manifestations associated with B12 deficiency are spinal cord manifestations (subacute combined degeneration of the spinal cord, ataxia, spasticity and abnormal gait), peripheral neuropathies, optic neuropathy and cerebrovascular diseases.
Title: Subacute Combined Degeneration of the Spinal Cord Due to Cronic Helicobacter pylori Infection.
(20) Also, many case studies have shown subacute combined degeneration after nitrous oxide anesthesia.
Another condition that is associated with a vitamin B deficiency, in this case B12, is subacute combined degeneration (SCD).
This is what the doctors said about Jason's condition: "Subacute combined degeneration of the spinal cord involving clearly the pyramidal tract as well as the corticospinal tracts based on MRI of the spine; Cyanocobalamin deficiency based on the very low level of his first B12 blood serum level; Nitrous oxide abuse; His hands are also getting weak in terms of his grip strength.
All objective studies have concluded that vitamin B12 has no appelite-stimulating properties and no role in neurological disorders other than subacute combined degeneration occurring in pernicious anaemia or other forms of vitamins B12 deficiency (Herbert, 1977) yet it is pathetic to note that vitamin B12 (Methycobal) is imported in Pakistan, wasting precious foreign exchange and promoted with information for all sorts of conditions including every type of neuropathy, weakness, anorexia and lethargy.

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