TGF-[alpha] is a 50 amino acid mitogenic polypeptide that has been detected from a variety of exocrine glands of body including lacrimal glands, pancreas and in the striated ducts
of both human submandibular and sublingual salivary glands (Yasui et al., 1992; Mogi et al., 1995; Humprey-Beher et al., 1994; Chiang et al., 2001; Ogbureke et al., 1995; Dernyk, 1988).
The connective tissue in humans, rats and mice is introduced and surrounds each glandular structure, being represented mainly by limited collagenous tissue available in irregular bundles at the level of the intercalated and striated ducts and more abundant collagenous tissue at the excretory level, accompanied by fibroblasts among the fibers (Fig.
Like the human salivary glands (Amano, 2011; Bruel et al., 2015), the duct system in rodents and rabbits is made up of intercalated ducts (ID), striated ducts (SD), excretory ducts (ED) and main excretory ducts, with these last ones leading to the main excretory duct (MED) (Fig.
The intercalated and striated ducts
are well-developed in both species in both glands.
No DOG1 expression was seen in the myoepithelial cell, striated ducts
, or excretory ducts.
Objective: To study the histomorphological characteristics of human sublingual gland, specially of intercalated and striated ducts
TGF-[alpha] is expressed in ductal epithelium of SMG, striated ducts
in parotid gland and in SLG (Wu et al., 1993).
The myoepithelial cells were located at the base of the acinar cells as well as intercalated and striated ducts
, and were stellate in shape.
The striated ducts
had simple columnar epithelium while the excretory ducts had the pseudostratified columnar epithelium with goblet cells.
Microscopically, it was verified that the CTG glands showed hypertrophy of serous acini with adipocytes on the cytoplasm and on the mucous acini, and striated ducts
without any alteration.
1) consists of serous acini and intercalated and striated ducts
. The serous acini lay close of each other, separated only by thin capillaries and very scarce connective tissue.
There are intercalated ducts with cubical epithelium connecting the acini with the striated ducts
. The last ones, more numerous, ate enclosed by higher cubical or columnar epithelium, with more eosinonophilic cells and basal striations (Fig.