Schachner, "Unilateral striae distensae affecting the right axilla in a 16-year-old boy: brief report," Pediatric Dermatology, vol.
Kamer, "The unusually large striae distensae all over the body," Advances in Medical Sciences, vol.
(8) Genetic predisposition is also presumed, since striae distensae have been reported in monozygotic twins.
Compared to normal fibroblasts, expression of fibronectin and both type I and type III procollagen were found to be significantly reduced in fibroblasts from striae, suggesting that there exists a fundamental aberration of fibroblast metabolism in striae distensae. (22)
Physiologic skin changes in pregnancy include changes in pigmentation (in the form of melasma, linea nigra, secondary areola, localized or generalized hyperpigmentation), vascular system (such as palmar erythema, spider angiomas, varicosities), striae distensae and endocrine function, as well as, changes in hair and nails.
Striae distensae develop in up to 90% of women during the 6th and 7th month of pregnancy.8 In our study, striae were seen in 76% of cases and were more common in multigravida (67%) than in primigravida (33%).
Other changes seen were oral lesions seen in 46% cases, yellowish discoloration of skin seen in 40% cases, pruritis seen in 45% cases, striae distensae
seen in 36% cases, Taenia infection was seen in 29% cases, Petechiae, ecchymosis and bruising were seen in 19% cases, urticaria was seen in 18% cases, Xanthelasma was seen in 8% cases, dermatitis was seen in 7% cases and vitiligo, dupuytren's contracture and spider naevi were seen in 3% cases each.
The ulcers in our patient were located and limited on the striae distensae
on the abdomen which is another distinctive feature.
Transverse striae distensae
in the lumbar area in father and two sons.
Intensely pruritic papules were seen within striae distensae
and in some patients the eruption extended to trunk and extremities.