Streptomyces hygroscopicus

a soil organism isolated on Easter Island; the source of rapamycin.

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Trichostatin produced from Streptomyces hygroscopicus is a well-known Histone deacetylase (HDAC) inhibitor, a validated target for the development of antitumor therapies (9).

Screening and Identification of Microbial Derivatives for Inhibiting Legumain: An In silico Approach

also observed an inhibition effect of phosphate on biosynthesis of turimycin, the secondary metabolite of Streptomyces hygroscopicus [11].

Optimization of Fermentation Conditions and Media for Production of Glucose Isomerase from Bacillus megaterium Using Response Surface Methodology

[28] reported that a 2.8-fold increase of antifungal production by Streptomyces hygroscopicus BS-112z could be accomplished by using the RSM approach.

Modification of Medium Composition for Enhancing the Production of Antifungal Activity from Xenorhabdus stockiae PB09 by Using Response Surface Methodology

Similarly, a higher agitation speed resulted in decreased DCW gain but increased antibiotic production by Streptomyces clavuligerus, Streptomyces hygroscopicus, Enterobacter cloacae, and Bacillus thuringiensis.

Significance of Heavy-Ion Beam Irradiation-Induced Avermectin B1a Production by Engineered Streptomyces avermitilis

Sirolimus (also known as rapamycin) is a macrocylic lactone immunosuppressive agent produced by Streptomyces hygroscopicus. It inhibits T-lymphocyte activation and proliferation due to antigen and cytokine stimulation, and reduces antibody production.

Sirolimus-induced lymphoedema

Rapamycin, an antifungal, anticancer, and immune-suppressing compound secreted by the bacterium Streptomyces hygroscopicus, is the basis for an anti-aging drug being developed by the Swiss pharmaceutical company Novartis.

Rapamycin, an anti-aging drug?

.Lipid and fatty acid composition of cytoplasmic membranes from Streptomyces hygroscopicus and its stable protoplast-type L form.

Poly-A3/4-hydroxy butyrate Depolymerase from Streptomyces lydicus MM10, Isolated from Wastewater Sample

Sirolimus is a macrolide-group antibiotic that is isolated from Streptomyces hygroscopicus (4).

Lymphedema treatment in a patient with a history of intestinal transplantation and mesenchymal stem cell transplantation/Ince barsak transplantasyonu ie mezenkimal kok hucre nakli hastasinda lenfodem tedaiisi

[27.] Igarashi Y, T Iida R, Yoshida and T Furumai Pteridic acids A and B, novel plant growth promoters with auxin-like activity from Streptomyces hygroscopicus TP-A0451.

Biocontrol of potato wilt by selective rhizospheric and endophytic bacteria associated with potato plant

The alpha glucosidase inhibitors (AGIs) were initially isolated from bacterial cultures or their derivatives: acarbose from Actinoplanes, miglitol, a semisynthetic derivative of 1-deoxynojirimycin, from Bacillus and Streptomyces sp.,and voglibose, from validamycin A, a product of Streptomyces hygroscopicus var.

Alpha glucosidase inhibitors

Rapamycin was early discovered in 1975 as an antifungal agent produced by Streptomyces hygroscopicus and has a great potency against Candida albicans (Vezina et al., 1975).

Enrichment of soymeal medium to increase the rapamycin production by Streptomyces hygroscopicus

Weiss et al, "Mannopeptimycins, new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98: antibacterial and mechanistic activities," Antimicrobial Agents and Chemotherapy, vol.

Production of bioactive compounds by actinomycetes and their antioxidant properties