Stone Man Disease

A rare idiopathic or autosomal dominant MIM 135100 condition of irregular penetration and pre-pubertal onset, in which connective/interstitial tissues undergo extensive fibrosis and heterotopic ossification of ligaments, tendons, muscle, fascia, aponeuroses and skin, first seen in late childhood as firm masses. The abnormal development of bone may lead to stiffness in affected areas and may also limit movement in affected joints, e.g., knees, wrists, shoulders, spine, and/or neck
DiffDx Osseous metaplasia, myositis ossificans, extraskeletal osteosarcoma
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Paul, 22, is one of only a handful of people in the world who are victims of the condition, known as "stone man disease." It has left Paul's torso, right side and left arm as hard as rock.