disease-modifying antirheumatic drug

(redirected from Steroid-sparing agent)

disease-modifying antirheumatic drug (DMARD)

a classification of antirheumatic agents referring to their ability to modify the course of disease, as opposed to simply treating symptoms such as inflammation and pain. Agents in this group include auranofin, azathioprine, cycloSPORINE, gold salts, hydroxychloroquine, leflunomide, methotrexate, D-penicillamine, and sulfasalazine.

disease-modifying antirheumatic drug

DMARD Rheumatology Any agent–eg, azathioprine, gold, cyclophosphamide, hydroxychloroquin, and MTX–which slows the rate of joint destruction in rheumatoid arthritis

disease-modifying antirheumatic drug

Abbreviation: DMARD
A drug that is used to treat rheumatoid arthritis and acts more slowly but more effectively than nonsteroidal anti-inflammatory drugs. Such drugs include hydroxychloroquine, methotrexate, and tumor necrosis factor inhibitors.
Synonym: slow-acting antirheumatic drug
See also: drug
References in periodicals archive ?
It underscores the importance of using thalidomide as a steroid-sparing agent to prevent adverse events associated with long-term steroid use.
To avoid complications of long-term topical corticosteroid use, including dermal atrophy, periodically switch to a steroid-sparing agent, such as calcipotriol ointment or topical pimecrolimus.
It summarizes ten years experience in treating INS with MMF in our centre, and it evaluates the safety and effectiveness profile of MMF as a steroid-sparing agent.
3,4) Azathioprine is the most commonly used steroid-sparing agent.
The patient was advised to continue treatment with 15mg of steroids and to commence with a steroid-sparing agent, Mycophenolate Mofetil at 500mg bds, and to employ self-care methods such as meditation, given the autoimmune nature of Birdshot.
NEW ORLEANS -- Colchicine is an effective steroid-sparing agent that can be used to treat refractory chronic idiopathic urticaria, based on data from a review of adults who received colchicine for CIU from 2003 to 2008.
Methotrexate has been used as a steroid-sparing agent, with varying success.
When you use a steroid-sparing agent like topical pimecrolimus in combination with a steroid, it helps reduce the need for steroid and helps kids get under better control.
Thalidomide is a double-edged weapon; although its use has been associated with devastating consequences such as phocomelia (when used in pregnant women), is extremely useful as a steroid-sparing agent.
Mycophenolate mofetil may serve as a steroid-sparing agent for sarcoidosis.
Methotrexate is an option for those who do not respond to prednisone or are in need of a steroid-sparing agent secondary to side effects (SOR: C).

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