CLEC11A

(redirected from Stem Cell Growth Factor)
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CLEC11A

A gene on chromosome 19q13.3 that encodes a C-type lectin domain protein expressed in bone, cartilage and bone marrow, which stimulates the proliferation and differentiation of haematopoietic stem cells. CLEC11A acts synergistically with other cytokines, such as IL3, GCSF, GMCSF and FLT3 ligand. CLEC11A suppresses SCF-stimulated erythrocyte proliferation.
References in periodicals archive ?
Minerva is the first company to generate human naive state iPS cells using a single, naturally occurring human stem cell growth factor. Previous attempts to grow human stem cells in the elusive naive state, which used cocktails of biochemical inhibitors and mouse growth factors, were prone to develop abnormal karyotype.
Minerva's proprietary primitive stem cell growth factor increases the efficiency of making human iPS cells, which greatly reduces the time and the cost of making iPS cells for research or for personalized stem cell banking.