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(vuh-lare-ee-en) ,


(trade name),


(trade name),


(trade name),


(trade name),

Belgium Valerian

(trade name),

Common Valerian

(trade name),

Fragrant Valerian

(trade name),

Garden Heliotrope

(trade name),

Garden Valerian

(trade name),

Indian Valerian

(trade name),

Mexican Valerian

(trade name),

Pacific Valerian

(trade name),


(trade name),


(trade name),

Valeriana officinalis

(trade name),

Valerianae radix

(trade name),

Valeriana rhizome

(trade name),


(trade name)


Therapeutic: antianxiety agents


May increase concentrations of the inhibitory CNS transmitter GABA.

Therapeutic effects

Improvement in sleep quality.


Absorption: Unknown.
Distribution: Unknown.
Metabolism and Excretion: Unknown.
Half-life: Unknown.

Time/action profile

PO30–60 min2 hrunknown


Contraindicated in: Pregnancy and lactation.
Use Cautiously in: Alcohol use (may have additive sedative effects); Surgery (discontinue use 2 weeks prior to elective procedures).

Adverse Reactions/Side Effects

Central nervous system

  • drowsiness
  • headache


  • dry mouth


  • Benzodiazepine-like withdrawal symptoms with discontinuation after long-term use


Additive CNS depression with alcohol, antihistamines, anesthetic agentssedative hypnotics and other CNS depressants.Alcohol-containing preparations may interact with disulfiram and metronidazole.Additive sedative effects can occur when used with herbal supplements with sedative properties such as kava, l-tryptophan, melatonin, SAMe, and St. John's wort.
Oral (Adults) Tea—1 cup tea 1–5 times daily. Tea is made by steeping 2–3 g root in 150 mL boiling water for 5–10 min then straining. Tincture—1–3 mL 1–5 times daily. Extract—400–900 mg up to 2 hours before bedtime or 300–450 mg divided tid.


Capsules: OTC
Extract: OTC
Tea: OTC
Tincture: OTC

Nursing implications

Nursing assessment

  • Assess degree of anxiety and level of sedation prior to and periodically throughout therapy.
  • Assess sleep patterns.
  • Assess response in the elderly population where drowsiness and loss of balance may pose a significant risk for injury.

Potential Nursing Diagnoses

Anxiety (Indications)
Risk for injury (Side Effects)


  • Take one to two hours before bedtime if used for nighttime hypnotic.
  • Administer orally three to five times daily to control anxiety.

Patient/Family Teaching

  • Encourage patients to avoid stimulants such as caffeine and to provide an environment that promotes restful sleep.
  • May cause drowsiness. Caution patient to avoid driving or other activities requiring alertness until response to drug is known.
  • Caution patient to avoid use of alcohol and other medications or herbals that have a sedative effect; may increase drowsiness.
  • Advise patients to discontinue 2 weeks prior to elective surgical procedures.
  • Inform patients not to take this herbal supplement if pregnant or breast-feeding.
  • Notify patients that dependence with withdrawal symptoms may develop with prolonged use.

Evaluation/Desired Outcomes

  • Decreased anxiety level.
  • Improvement in sleep with a feeling of restfulness without drowsiness upon awakening.




Any of several plants, such as self-heal or valerian, used in herbal medicine and reputed to have broad healing powers.


(1) Heal-all, see there; Prunella vulgaris.
(2) Valerian, see there; Valeriana officinalis.
References in periodicals archive ?
En la Depresion del Balsas ubicada dentro de la Sierra Madre del Sur coinciden Asterohyptis, Hyptis, Salvia, Stachys y Vitex (Figs.
Considering the high number of existing Labiatae species and diversity and broad distribution of some of the larger genera, such as Aegiphila, Clerodendrum, Hyptis, Ocimum, Plectranthus, Salvia, Scutellaria and Stachys (Table 1), then it is evident that additional systematic prospecting work is required for having a broader panorama about the presence of mucilage and lectin in the nultles of different species.
Turner 18213 Lamiaceae Scutellaria hintoniorum Henrickson 18294 Lamiaceae Stachys hintoniorum B.
Labiatae, lectin, mucilage, Aegiphila, Hyptis, Lepechinia, Ocimum, Salvia, Scutellaria, Stachys.
Inhibition of prostaglandin E2 and leukotriene C4 in mouse peritoneal macrophages and thromboxane B2 production in human platelets by flavonoids from Stachys chrysantha and Stachys candida.
Other plants with a similar foliage but not as large individual leaves are Stachys byzantina, Ballota acetabulosa and pseudodictamnus.
The Romans gleaned their grain from the Greeks, who called the star Stachys, a name cut from the same grain.
Related Family Members in Book: Leonotis, Mentha, Molucella, Monarda, Perovskia, Physostegia, Rosmarinus, Salvia, Solenostemon, Stachys, and Thymus
Stipa tenuissima | |Mediterranean-looking plants with silvery or hairy foliage - santolina (cotton lavender), verbascum, phlomis (Jerusalem sage) stachys (lamb's ears), ballota, convolvulus and lavender are all hardy
Lamb's ears, Stachys byzantia: As its common name suggests, its downy leaves resemble the ears of a lamb.