SH2 domain(redirected from Src homology 2 domain-containing)
SH2 domainA modular, circa-100-amino acid domain which binds to specific phospho-containing peptide motifs; SH2 is found in adaptors, kinases, phosphatase, Ras signalling, scaffolds, transcription, ubiquination. It is involved in cytoskeletal regulation, phospholipid second messenger signalling, and in signal regulation.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.