Squamous cells

Squamous cells

Thin, flat cells on the surfaces of the skin and cervix and linings of various organs.
Mentioned in: Cervical Cancer

Patient discussion about Squamous cells

Q. what is the most accurate pathological test to identify the primary source of a cystic mass in the neck? the mass was removed. Pathologist was unable to identify the source and diagnosed the mass as a branchilogic carcinmoa (which is extremely rare, if exists at all). Therefore, I am looking for the most updated test and examinations that can be applied to blocks of the mass and determine their origin (primary source)

A. Pathologic examinaions under a microscope are the most accurate ones there are, and sometimes even they don't help to identify the cell types. I do not have any other ideas on other tests you can do, and I believe you should follow the treatment your doctors will advise you based on this diagnosis they have made.

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References in periodicals archive ?
Squamous cell carcinoma (SCC) is an uncontrolled growth of abnormal cells arising in squamous cells, which compose most of skin's upper layers (epidermis).
The mass contained a tumour composed of atypical malignancy squamous cells in sheets.
Most head and neck cancers are squamous cell carcinomas that begin in the flat, squamous cells that make up the thin surface layer of the structures in the head and neck.
Histologically, these tumors are characterized by dense, superficial keratinization, often forming "church spires" of orthokeratotic and parakeratotic squamous cells extending upward from the surface (Figure 4, A).
Tumor suppressor genes and oncogenes are pri- marily responsible for genetic alterations at molecular level and thus are responsible for progression of normal epithelial cells to dysplastic squamous cells.
Editor's Note: Squamous cells occur in the outermost layers of the skin, as well as in the lining of the digestive tract and other areas.
1 These squamous cells form the lining epithelium of skin, oral cavity, oesophagus, rectum, vagina etc.
Squamous cells are the main part of the outermost layers of the skin, and SCC is one of the major forms of skin cancer.
The diagnosis is established when malignant cells are entirely of squamous cells, and overlying skin malignancies or other primary sites of squamous cell carcinoma have been excluded2.
The origin of the squamous cells within the breast is unknown.
At that time, biopsy revealed only squamous cells and the preliminary diagnosis was oesophageal carcinoma.

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