Squamous cells

Squamous cells

Thin, flat cells on the surfaces of the skin and cervix and linings of various organs.
Mentioned in: Cervical Cancer

Patient discussion about Squamous cells

Q. what is the most accurate pathological test to identify the primary source of a cystic mass in the neck? the mass was removed. Pathologist was unable to identify the source and diagnosed the mass as a branchilogic carcinmoa (which is extremely rare, if exists at all). Therefore, I am looking for the most updated test and examinations that can be applied to blocks of the mass and determine their origin (primary source)

A. Pathologic examinaions under a microscope are the most accurate ones there are, and sometimes even they don't help to identify the cell types. I do not have any other ideas on other tests you can do, and I believe you should follow the treatment your doctors will advise you based on this diagnosis they have made.

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References in periodicals archive ?
Tumor suppressor genes and oncogenes are pri- marily responsible for genetic alterations at molecular level and thus are responsible for progression of normal epithelial cells to dysplastic squamous cells.11 Various proliferative and apoptotic pathways are involved in normal cell cycle and growth.12 When tumor suppressor genes get inactivated and oncogenes are activated these proliferative and apoptotic pathways are de-regulated which leads to tumor development.
All normal squamous cells can secrete PTHrP but only certain squamous cell tumors result in hypercalcemia [3].
Editor's Note: Squamous cells occur in the outermost layers of the skin, as well as in the lining of the digestive tract and other areas.
Squamous cell carcinoma (SCC) is a malignant neo- plasm of epithelial cells exhibiting squamous differentiation as characterised by the formation of kera- tin and the presence of intercellular bridges.1 These squamous cells form the lining epithelium of skin, oral cavity, oesophagus, rectum, vagina etc.
Squamous cells are the main part of the outermost layers of the skin, and SCC is one of the major forms of skin cancer.
It was composed of strands, cords and nests of squamous cells. These cells showed pleomorphic hyperchromatic nuclei.
Contribution of cytopathology to the diagnosis of oral squamous cells carcinoma.
Squamous cell carcinoma begins in the squamous cells, which are thin, flat cells that resemble fish scales under a microscope.
At that time, biopsy revealed only squamous cells and the preliminary diagnosis was oesophageal carcinoma.
(1) Primary squamous cell carcinoma (SCC) of the thyroid is a sporadic malignant disease because the thyroid lacks squamous cells.
Squamous cells can be found in the thyroid from persistence of thyroglossal ducts or brachial pouch-derived structures or from squamous metaplasia in Hashimoto's thyroiditis.
Cytologic study of the sample revealed rare ductal cells, few atypical cells, and anucleated squamous cells in a proteinaceous background.

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