carcinoma (SCC) is an uncontrolled growth of abnormal cells arising in squamous cells
, which compose most of skin's upper layers (epidermis).
The mass contained a tumour composed of atypical malignancy squamous cells
Most head and neck cancers are squamous cell
carcinomas that begin in the flat, squamous cells
that make up the thin surface layer of the structures in the head and neck.
Histologically, these tumors are characterized by dense, superficial keratinization, often forming "church spires" of orthokeratotic and parakeratotic squamous cells
extending upward from the surface (Figure 4, A).
Tumor suppressor genes and oncogenes are pri- marily responsible for genetic alterations at molecular level and thus are responsible for progression of normal epithelial cells to dysplastic squamous cells
Editor's Note: Squamous cells
occur in the outermost layers of the skin, as well as in the lining of the digestive tract and other areas.
1 These squamous cells
form the lining epithelium of skin, oral cavity, oesophagus, rectum, vagina etc.
are the main part of the outermost layers of the skin, and SCC is one of the major forms of skin cancer.
It was composed of strands, cords and nests of squamous cells
The diagnosis is established when malignant cells are entirely of squamous cells
, and overlying skin malignancies or other primary sites of squamous cell
carcinoma have been excluded2.
The origin of the squamous cells
within the breast is unknown.
At that time, biopsy revealed only squamous cells
and the preliminary diagnosis was oesophageal carcinoma.