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A virus genus encompassing a poorly characterized group of retroviruses that cause vacuolation (foaming) of cultured cells; usually cause persistent but silent infections in their natural hosts and no diseases caused by these agents have been identified.


/Spu·ma·vi·rus/ (spu´mah-vi″rus) foamy viruses; a genus of nonpathogenic viruses of the subfamily Spumavirinae (family Retroviridae) that induce persistent infection in humans, primates, cats, cattle, and hamsters.


A genus of retroviruses occasionally transmitted to humans after exposure to the blood or body fluids of infected animals (e.g., apes, cats, or cattle).


a member of the subfamily Spumavirinae.
References in periodicals archive ?
HTLV-1 and HTLV-2) vaccine; 3) Spumavirus vaccine; 4) Type D retrovirus vaccine; and 5) A vaccine against most known retroviruses (RETROVAX),
ONASCO decided to manufacture small quantities of totally synthetic vaccines to other human and monkey retroviruses, besides HIV-1 and HIV-2, which include: 1) The human T-lymphotropic retrovirus types 1 and 2 (HTLV-1 and HTLV-2), which have been associated with certain diseases and are endemic in Japan; 2) The spumavirus (foamy virus), which has been isolated from both humans and monkeys; 3) The type D retrovirus, which causes most of the simian AIDS (SAIDS) in captive monkeys and has recently been isolated from a human with AIDS; and 4) a vaccine against many known retroviruses (RETROVAX), which includes HTLV-1, HTLV-2, spumavirus, and type D retroviruses.