Spumavirus | definition of Spumavirus by Medical dictionary
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A virus genus encompassing a poorly characterized group of retroviruses that cause vacuolation (foaming) of cultured cells; usually cause persistent but silent infections in their natural hosts and no diseases caused by these agents have been identified.
A genus of retroviruses occasionally transmitted to humans after exposure to the blood or body fluids of infected animals (e.g., apes, cats, or cattle).
References in periodicals archive
Characterization of spumavirus infection in humans is limited.
Sequencing of the PCR products from one region indicated that the sequences from each worker were distinct from each other; however, all three demonstrated [is greater than] 80% homology to known spumavirus sequences of NHP origin.
The family includes seven genera: alpharetrovirus, betaretrovirus, gammaretrovirus, deltaretrovirus, epsilonretrovirus, lentivirus (LV), and spumavirus
. Gammaretroviruses and more commonly LV have been used as retroviral vectors.