sporozoite

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Related to Sporozoites: Merozoites

sporozoite

 [spor″o-zo´īt]
a spore formed after fertilization; any one of the sickle-shaped nucleated germs formed by division of the protoplasm of a spore of a sporozoan organism. In malaria, the sporozoites are the forms of the plasmodium that are liberated from the oocysts in the mosquito, that accumulate in the salivary glands, and that are transferred to humans when the mosquito feeds.

spo·ro·zo·ite

(spō'rō-zō'īt),
One of the minute elongated bodies resulting from the repeated division of the oocyst during sporogony. In the case of the malarial parasite, it is the form that is concentrated in the salivary glands and introduced into the blood by the bite of a mosquito; it enters the liver cells (exoerythrocytic cycle), the progeny of which, the merozoites, infect the red blood cells to initiate clinical malaria.
[sporo- + G. zōon, animal]

sporozoite

/spo·ro·zo·ite/ (-zo´īt) the motile, infective stage of certain protozoa that results from sporogony.

sporozoite

(spôr′ə-zō′īt′)
n.
Any of the cells that are released from the oocyst of an apicomplexan parasite and invade a new host cell.

sporozoite

[spôr′əzō′īt]
Etymology: Gk, sporos + zoon, animal
any of the cells resulting from the sexual union of spores during the life cycle of a sporozoon. It refers specifically to the elongated nucleated cells produced by the multiple fission of the zygote contained in the oocyst in the female Anopheles mosquito during the sexual reproductive stage of the life cycle of the malarial parasite Plasmodium. On release from the oocyst, the sporozoites migrate to the salivary glands of the mosquito, where they are transmitted to humans and develop within the parenchymal cells of the liver as merozoites. Also called falciform body. See also malaria, Plasmodium.

spo·ro·zo·ite

(spōr'ō-zō'īt)
One of the minute elongated bodies resulting from the repeated division of the oocyst during sporogony. In the case of the malarial parasite, it is the form that is concentrated in the salivary glands and introduced into the blood by the bite of a mosquito; it enters the liver cells (exoerythrocytic cycle); its progeny, the merozoites, infect the red blood cells to initiate clinical malaria.
[sporo- + G. zōon, animal]

sporozoite

A motile reproductive form of a SPOROZOON that has been released from an oocyst and is ready to penetrate a new host cell, as in malaria transmission.

sporozoite

any of the very small mobile spores formed by multiple fission of a protozoan zygote, as in the MALARIA PARASITE.

sporozoite

a spore formed after fertilization; a sickle-shaped nucleated germ formed by division of the protoplasm during sporogony (asexual replication) of an apicomplexan parasite. The sporozoite is an infective stage (e.g. Eimeria, Cryptosporidium).
References in periodicals archive ?
By 1983, the 7G8 strain (chloroquine resistant) was cloned from a Brazilian patient sample and, in regular production at WRAIR, showed low numbers of oocysts and sporozoites but with greater consistency than any other strain.
Expression of the two types of S gene has been confirmed by sequencing of cloned reverse transcriptase/polymerase chain reaction fragments amplified from sporozoite rRNA (Li and McCutchan, data not shown).
This is an important advance," he says, noting that the vaccine induces an immune onslaught that kills the malaria parasite in its infective sporozoite stage.
Results reported in the journal Science show that several jabs of the new whole sporozoite vaccine, given over a period of months, can provide total protection against malaria.
If the sporozoite injected by a mosquito into a human host develops directly into a tissue schizont, the incubation period between the initial infection and the onset of symptoms is short, typically from 10 days to 4 weeks, resulting in an early primary attack.
Inside the liver, the sporozoites change form and then grow and divide into thousands of merozoites.
DELETING THE PARASITE'S GENES Kappe's team is seeking to interrupt this process at a critical stage and has found a way of genetically modifying the sporozoites to delete key genes from their DNA, so that while they still make it into the liver where they trigger a strong immune response, they are also genetically programmed to die off there.
It is not feasible to immunize large numbers of humans by bite of mosquitoes carrying sporozoites, and it was considered impossible to manufacture a sporozoite vaccine that met regulatory standards.
A single specimen harbored, in its salivary glands, sporozoites identified as those of Plasmodium.
Oocysts of 4-5 [micro]m in diameter, red in color and containing sporozoites were considered positive for C.
RTS,S contains pieces of sporozoites, which prepare the immune system to attack this parasite form.
Observations among those that were caught inside the rooms sprayed with etofenprox for sporozoites revealed zero from the experimental village and 1/353 from the control village.