spindle cell

(redirected from Spindle cells)
Also found in: Dictionary.
Related to Spindle cells: sarcoma, spindle cell carcinoma, Spindle fibers

spin·dle cell

a fusiform cell, such as those in the deeper layers of the cerebral cortex.
Farlex Partner Medical Dictionary © Farlex 2012

spindle cell

n.
A spindle-shaped cell characteristic of certain tumors.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

spindle cell

A generic term for an elonged and/or fusiform cell, regardless of origin.
 
Lineage
Mesenchymal, epithelial, lymphoproliferative; in general, mesenchymal spindle cells—e..g., fibroblasts and myofibroblasts—are benign and are normally found in stromal tissues; spindled epithelial cells are uncommon and usually seen in poorly differentiated squamous cell carcinoma, hairy cell leukaemia, and various sarcomas.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

spin·dle cell

(spin'dĕl sel)
A fusiform cell, such as those in the deeper layers of the cerebral cortex.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Matrix-producing carcinoma is defined as an invasive breast carcinoma with a direct transition of carcinoma to cartilaginous or osseous matrix without an intervening spindle cell component.
Our case showed a mixed population of spindle cells (predominantly) and epithelioid/plasmacytoid cells, demonstrating nuclear pleomorphism, coarse and clumped chromatin, variable inconspicuous to multiple prominent small nucleoli, and occasionally bi-nucleated tumour giant cells/ bizarre nuclei; and lacks the main cytological features elaborated above of conventional melanoma.
The name hemangiopericytoma is frequently used in veterinary medicine to denominate a histological feature created by a variety of spindle cell tumors arranged in a whorl pattern, rather than a specific tumor of the pericytes (GROSS et al., 2005), due to the difficulty in identifying pericytes by their morphology and immunophenotype (GOLDSCHMIDT & HENDRICK, 2002; GROSS et al., 2005).
Spindle cells show a fascicular or storiform pattern of growth, indistinguishable from a true sarcoma (Figures 3(a) and 3(b)).
However, the presence of spindle cells with a storiform arrangement was an important feature in the histoid form that was not present in the lepromatous form.
Pseudoangiomatous stromal hyperplasia (PASH), first reported by vuitch et al., is a benign proliferative disease of the breast.1 It is characterized by proliferation of stromal spindle cells with an intervening network of complex anastomosing channels lined by slender spindle cells.2 PASH usually presents as painless, single or multiple, palpable breast masses, or as continuous breast enlargement.3 In this report, we present a case of a 25 year old lady who presented with painless single swelling of her right breast.
(2) Microscopically, multinucleated giant cells were found dispersed regularly among the mononuclear spindle cells stroma, without any areas of aggregation.
Spindle cell lipoma of the oral cavity: report of a case.
In reporting the clinicopathological features of 5 intestinal IMFTs (I-IMFTs) that were identified in the archives of the University of KwaZulu-Natal teaching hospitals over a 4-year period, we compare and contrast the clinicopathological findings with those recorded globally, and discuss the associated nosologic controversies and aetiopathogenetic advances posed by these heterogeneous spindle cell neoplasms.
Spindle cell squamous cell carcinoma (SCSCC) is a squamous cell carcinoma (SCC) with a biphasic appearance, yielding a spindle cell transformation.
Partially regressed lesions exhibit a significant reduction of spindle cells. Completely regressed lesions are characterised by an absence of detectable spindle cells, often accompanied by a slight increase in capillaries of the superficial plexus.
His second report confirmed the benign diagnosis and included mitotic count and spindle cells in the description of the microscopic exam.