spherocytosis

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Related to Spherocytes: Heinz bodies, target cells

spherocytosis

 [sfe″ro-si-to´sis]
the presence of spherocytes in the blood.
hereditary spherocytosis a congenital hereditary form of hemolytic anemia characterized by spherocytosis, abnormal fragility of erythrocytes, jaundice, and splenomegaly.

sphe·ro·cy·to·sis

(sfē'rō-sī-tō'sis),
Presence of spheric red blood cells in the blood.
Synonym(s): microspherocytosis
[spherocyte + G. -osis, condition]

spherocytosis

/sphe·ro·cy·to·sis/ (sfēr″o-si-to´sis) the presence of spherocytes in the blood.
hereditary spherocytosis  a congenital hereditary form of hemolytic anemia characterized by spherocytosis, abnormal fragility of erythrocytes, jaundice, and splenomegaly.

spherocytosis

[sfir′ōsītō′sis]
the abnormal presence of spherocytes in the blood. Compare elliptocytosis.
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Spherocytosis

spherocytosis

Congenital spherocytic anemia, congenital spherocytosis, hereditary spherocytosis, spherocytic anemia Hematology A rare–1:5000 AD condition characterized by chronic hemolytic anemia with ↑ osmotic fragility and autohemolysis of globose RBC due to various defects in RBC membrane proteins Clinical Infants may be jaundiced; other Sx may be seen in older Pts fatigue, weakness, SOB, anemia, intermittent jaundice, splenomegaly, gallstones, leg ulcers Management Splenectomy. Cf Elliptocytosis.

sphe·ro·cy·to·sis

(sfēr'ō-sī-tō'sis)
Presence of spherelike red blood cells in the blood.
[spherocyte + G. -osis, condition]

spherocytosis

A blood disorder in which the red cells are unusually small and spherical. In hereditary spherocytosis the red cells are fragile and burst easily, causing ANAEMIA.

sphe·ro·cy·to·sis

(sfēr'ō-sī-tō'sis)
Presence of spheric red blood cells in blood.
[spherocyte + G. -osis, condition]

spherocytosis

the presence of spherocytes in the blood.
References in periodicals archive ?
9 Platelets * * * Mean Platelet Volume * * * Neutrophils 7 29 58 Bands 54 50 35 Lymphocytes 10 9 5 Monocytes 7 0 2 Metamyelocyte 12 9 0 Myelocyte 8 2 0 Promyelocyte 2 1 0 Nucleated Red Blood Cells 2 0 2 Polychromasia present [dagger] [dagger] Poikilocytosis present [dagger] present Anisocytosis present [dagger] present Microcytes present [dagger] [dagger] Spherocytes present [dagger] [dagger] Mega-thrombocytes present present [dagger] Absolute Neutrophils 3.
It is well known that erythrocytes change into spherocytes by a substantial loss of membrane surface through vesiculation and MV generation.
In the presence of a large number of spherocytes in the peripheral blood film, a major alternative differential diagnosis was autoimmune haemolysis (which can mimic HS).
6 anisocytosis target cells spherocytes fragments NRBC Patient 3 target cells 15 24 month spherocytes old, G6PD polychromasia deficient blister cells Patient 4 9 11 month old Patient 5 5.
While hospitalized, the dog had mild anemia without spherocytes, moderate to severe thrombocytopenia with large platelets, moderate leukocytosis with a left shift, a moderate hypokalemia, a mild hypoglycemia, and hypoproteinemia.
Red blood cell morphology was suggestive of a microangiopathic process: microscopic examination indicated that five of the eight infants had mild to moderate (1+ to 2+) hemolysis characterized by the presence of microcytes, burr cells, spherocytes, and bizarre fragments.
echinocytic RBCs, spherocytes, and necrobiotic leucocytes).
Medical conditions such as microcytic anemia, sickle cell anemia, presence of spherocytes and rouleaux, rheumatoid arthritis, chronic infections, Hodgkin's disease, and multiple myeloma affect results.
Peripheral blood smear showed, Howell jolly bodies, target cells and spherocytes.
WBC Toxic granulations 28 Dohle bodies 5 Vacuolations 38 Smudge cells 32 Clefted lymphocytes 10 Hairy projections 2 Auer rods 2 RBC Anisocytosis 54 Poikilocytosis 31 Microcytosis 7 Macrocytosis 2 Hypochromasia 3 Polychromasia 35 Echinocytes (burr cells) 19 Dacrocytes (teardrops) 16 Spherocytes 6 Target cells 2 Acanthocytes 1 Ovalocytes 28 Schistocytes 5 Stomatocytes 2 Howell-Jolly bodies 1 Basophilic stipplings 5 Platelet Clumped platelets 3 Platelet satellitosis 5 Large platelets 8 Giant platelets 8 Overall Cell Morphology Code Concordance, Overall Type % Concordance, % WBC Toxic granulations 78.