spermatogonium

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spermatogonium

 [sper″mah-to-go´ne-um] (Gr.)
an undifferentiated male germ cell, originating in a seminal tubule and dividing into two spermatocytes.

sper·ma·to·go·ni·um

(sper'mă-tō-gō'nē-ŭm),
The primordial male cell derived by mitotic division from the yolk sac that migrates into the developing testes. Subsequent to puberty, it differentiates by increasing several times in size to become a primary spermatocyte.
See also: spermatid.
[spermato- + G. gonē, generation]

spermatogonium

(spər-măt′ə-gō′nē-əm, spûr′mə-tə-)
n. pl. spermatogo·nia (-nē-ə)
Any of the cells that give rise through mitosis to the spermatocytes and are found in the testes of vertebrates.

sper·mat′o·go′ni·al (-nē-əl) adj.

sper·ma·to·go·ni·um

, spermatogone (spĕr'mă-tō-gō'nē-ŭm, -mă-tō-gōn)
The undifferentiated male sex cell derived by mitotic division from a primordial germ cell; increasing several times in size, it becomes a primary spermatocyte.
See also: spermatid
Synonym(s): spermatoblast.
[spermato- + G. gonē, generation]

spermatogonium

an early diploid stage of male GAMETO GENESIS.
References in periodicals archive ?
In other researches, Oct-4 was used as a specific marker for identification of bovine spermatogonial stem cells (15)' (28).
Spermatogonial stem cells and Sertoli cells, obtained from human testis biopsies by a two-step enzymatic digestion method, were purified using fluorescence- activated cell-sorting and daturastramonium-lectin, and were cultured separately.
In 4 of 6 men, Xenotransplantaion to mice demonstrated the presence of functional spermatogonial stem cells, even after prolonged in vitro culture.
Ogonuki et al., "ROS are required for mouse spermatogonial stem cell self-renewal," Cell Stem Cell, vol.
Spermatogonial stem cell biology in the bull: development of isolation, culture, and transplantation methodologies and their potential impacts on cattle production.
Importantly, she also observed an 80% reduction in spermatogonial stem cell regeneration.
Imatinib has deleterious effects on differentiating spermatogonia while sparing spermatogonial stem cell self renewal.
The important aspects of spermatogonial stem cells resulted in their widespread use in reproductive technologies such as spermatogonial stem cell transplantation and transgenesis in species wherein embryonic stem cells are not available and somatic cell nuclear transfer and reprogramming pose several problems 16.3031.
By manipulating STAT3 - a protein that signals stem cells to decide differentiation - researchers identified a key regulator of spermatogonial stem cell self-renewal.
The remaining seven articles detail protocols of in vitro culture and applications, including spermatogonial germ cell transplantation, ectopic grafting of mammalian testis tissue, and deriving mouse spermatogonial stem cell lines.