SPAG9

(redirected from Sperm-specific protein)

SPAG9

A gene on chromosome 17q21.33 that encodes sperm-associated antigen 9, a member of the JNK-interacting protein (JIP) group of scaffold proteins, which selectively mediates JNK signalling by aggregating specific components of the MAPK cascade to form a functional JNK-signalling module.
References in periodicals archive ?
In a HFEA-approved procedure, human eggs were injected with an egg-activating sperm-specific protein ('PLC-zeta') and then imaged over a period of several hours.