SPAM1

(redirected from Sperm surface protein PH-20)

SPAM1

A gene on chromosome 7q31.3 that encodes sperm-adhesion molecule 1 involved in sperm-egg adhesion, which helps sperm penetrate the layer of cumulus cells of an ovum by digesting the hyaluronic acid matrix formed before ovulation.
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References in periodicals archive ?
McDonald et al., "Effects of scrotal heating on sperm surface protein PH-20 expression in sheep," Molecular Reproduction and Development, vol.