tetanospasmin

(redirected from Spasmogenic toxin)
Also found in: Encyclopedia.

tetanospasmin

 [tet″ah-no-spaz´min]
the neurotoxic component of the tetanus toxin, which causes the muscle spasms of tetanus.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

tet·a·no·spas·min

(tet'ă-nō-spaz'min),
The neurotoxin of Clostridium tetani, which causes the characteristic signs and symptoms of tetanus; chief action is on the anterior horn cells, and the spasms seem to be due to action at inhibitory synapses.
Farlex Partner Medical Dictionary © Farlex 2012

tetanospasmin

Toxicology A 150 kD neurotoxin produced by Clostridium tetani, which is one of the most toxic substances known to man; it selectively blocks inhibitory nerve transmission from the spinal cord to the muscles, causing severe muscle spasms, which may be intense enough to tear muscle or cause compression fractures of the vertebrae; it evokes unrestrained muscle firing and sustained muscular contraction, causing lockjaw, dysphagia, or acute respiratory failure by tetany of the diaphragm. See Poisons.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

tet·a·no·spas·min

(tet'ă-nō-spaz'min)
The neurotoxin of Clostridium tetani, which causes the characteristic signs and symptoms of tetanus; chief action is on the anterior horn cells, and the spasms seem to be due to action at inhibitory synapses.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012