En el caso del reconocimiento de la presencia de Sonic hedgehog
(Shh) en las capas que constituyen el esbozo de iris, observamos que a los 17,5 dpc existe una inmunotincion positiva del morfogeno Shh en el primer segmento de la capa interna del iris.
The adventures of Sonic Hedgehog
in development and repair.
Jessell, "Two critical periods of Sonic Hedgehog
signaling required for the specification of motor neuron identity," Cell, vol.
Ruther, "Evidence for genetic control of Sonic hedgehog
by Gli3 in mouse limb development," Mechanisms of Development, vol.
myocardial gene therapy: Tissue repair through transient reconstitution of embryonic signaling.
is that signal, as we went on to demonstrate," Fuchs said.
Around the same time as the BBS result, Kathryn Anderson of Memorial Sloan-Kettering Cancer Center in New York City and colleagues were looking for genetic mutations that could scramble sonic hedgehog
signals in mice.
Citation: "Persistent Sonic Hedgehog
Signaling in Adult Brain Determines Neural Stem Cell Positional Identity;" Rebecca A.
In snake "gums," a gene called sonic hedgehog
lays out the toothy part of the body plan.
One such example is "sonic hedgehog
," a gene linked to holoprosencephaly.