(redirected from Somatotrophs)


a type of acidophil of the adenohypophysis that secretes growth hormone.


/so·mato·trope/ (so-mat´o-trōp) somatotroph.


, somatotrope (sō-mat'ō-trōf, -trōp)
A cell of the adenohypophysis that produces somatotropin.


References in periodicals archive ?
Mechanisms governing the release of growth hormone from acutely dispersed purified somatotrophs.
Cytochemical identification of human and murine pituitary corticotrophs and somatotrophs as APUD cells.
Melamed et al [106] suggest that estradiol and IGF-I, both generated from cells other than the somatotrophs, may exert antiapoptotic effects and thus possibly control the size of this somatotroph cells.
Possible interactions between gonadotrophs and somatotrophs in the pituitary of tilapia: apparent roles for insulin-like growth factor I and estradiol.
Direct pituitary effects of kisspeptin: activation of gonadotrophs and somatotrophs and stimulation of luteinising hormone and growth hormone secretion.
During aging there are several changes which contribute to the decline in GH/IGF-I including changes in signal to the somatotrophs from growth hormone releasing hormone, somatostatin and other factors such as body composition, exercise, diet and sleep.
In vitro studies have shown that glucocorticoids increase growth hormone gene expression and enhance growth hormone release from cultured rat pituitary somatotrophs (Evans et al.
Somatotrophs are one of five cell types within the pituitary gland and their major function is the secretion of GH.
Ontogrny of the sensitivity of the somatotrophs to TRH and growth hormone-releasing factor (GRF) in the embryonic and post-hatch chick.
However, it is unclear from this earlier report whether the pituitary damage is restricted to somatotrophs and results from the tumor burden or from the chronic toxicity of DEN.

Full browser ?