somatomedin
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Related to Somatomedins: Somatomedin C, Enamel lamellae
somatomedin
[so″mah-to-me´din]any of a group of peptides found in the liver and in other tissues which mediate the effect of growth hormone (somatotropin) on cartilage; they are responsible for uptake of sulfate and increased synthesis of collagen and other proteins by cartilage. Somatomedins also have insulinlike biologic actions and increase RNA synthesis and promote DNA synthesis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
so·ma·to·me·din
(sō'mă-tō-mē'din),One of several peptides; somatomedin peptide (MW about 4,000), also called insulinlike growth factor II, is synthesized in the liver and probably in the kidney; it is capable of stimulating certain anabolic processes in bone and cartilage, such as synthesis of DNA, RNA, and protein (including chondromucoprotein), and the sulfation of mucopolysaccharides; secretion and biologic activity of somatomedin is known to depend on somatotropin.
See also: insulinlike growth factor.
See also: insulinlike growth factor.
[somato, tropin + mediator + -in]
Farlex Partner Medical Dictionary © Farlex 2012
somatomedin
(sō-măt′ə-mēd′n, sō′mə-tə-)n.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
somatomedin
Any of a group of hormones that mediate the effects of growth hormone (formally, somatopropin):(1) Insulin-like growth factor-I (somatomedin C);
(2) Insulin-like growth factor-II (somatomedin A);
(3) Vitronectin (somatomedin B).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
so·ma·to·me·din
(sō'mă-tō-mē'din)A peptide synthesized in the liver, and probably also in the kidney, capable of stimulating certain anabolic processes in bone and cartilage, such as synthesis of DNA, RNA, and protein, and the sulfation of mucopolysaccharides; secretion or biologic activity of somatomedin is known to depend on somatotropin.
[somato, tropin + mediator + -in]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
so·ma·to·me·din
(sō'mă-tō-mē'din)One of several peptides; also called insulinlike growth factor II, is synthesized in the liver and probably kidney.
[somato, tropin + mediator + -in]
Medical Dictionary for the Dental Professions © Farlex 2012