SLC25A4

(redirected from Solute carrier family 25 member 4)

SLC25A4

A gene on chromosome 4q35 that encodes a mitochondrial solute carrier protein, which functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. SLC25A4 forms a homodimer embedded in the inner mitochondria membrane.

Molecular pathology
SLC25A4 mutations cause autosomal dominant progressive external ophthalmoplegia and familial hypertrophic cardiomyopathy.
References in periodicals archive ?
SLC25A4 (Solute carrier family 25 member 4) or ANT1 (Adenine nucleotide translocator 1) functions as a gated pore that translocates ADP and ATP between cytoplasm and mitochondria, regulating the intracellular energetic balance.

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