methylprednisolone

(redirected from Solumedrol)
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methylprednisolone

 [meth″il-pred-nis´o-lōn]
a synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant; also used as m. acetate and m. sodium succinate.

methylprednisolone

/meth·yl·pred·nis·o·lone/ (-pred-nis´ah-lōn) a synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant; also used as m. acetate and m. sodium succinate.

methylprednisolone

(mĕth′əl-prĕd-nĭs′ə-lōn′)
n.
A glucocorticoid used therapeutically primarily as an anti-inflammatory agent.

methylPREDNISolone

[-prednis′əlōn]
a glucocorticoid.
indications It is prescribed as an antiinflammatory drug and as an immunosuppressant to treat autoimmune disease, cancer, and other disease involving cells of the immune system. It is also administered to suppress graft-versus-host disease after bone marrow transplantation.
contraindications Fungal infections or known hypersensitivity to this drug prohibits its systemic use. Viral or fungal infections of the skin, impaired circulation, or known hypersensitivity to this drug prohibits its topical use.
adverse effects Among the more serious adverse effects of the systemic administration of the drug are upper GI bleeding and endocrine, neurological, fluid, and electrolyte disturbances. Skin reactions may result from topical administration of this drug.

methylprednisolone

A CORTICOSTEROID drug used in a wide range of conditions to control severe inflammation, treat allergies and replace stroid deficiencies. It is commonly used in depot form for long-term action. Brand names are Medrone, Depo-Medrone and Solu-Medrone.

methylprednisolone

a glucocorticoid with anti-inflammatory action similar to that of prednisolone. The acetate is often prepared in long-acting forms while the water-soluble, rapid-acting succinate is suitable for intravenous administration and is used in the treatment of shock.

methylprednisolone-21-dimethylaminoacetate
a long-acting glucocorticoid, used in the treatment of dermatoses and allergic conditions.
References in periodicals archive ?
Clinical data and the opinions of interviewed thought leaders indicate that Janssen Biotech/Merck/Mitsubishi Tanabe's Remicade, the sales-leading agent in the ulcerative colitis market, offers comparable efficacy in inducing remission compared with oral prednisone and intravenous cyclosporine (Novartis's Sandimmune, generics) but is at a disadvantage to intravenous methylprednisolone (Pfizer's SoluMedrol, Sanofi's Urbason, generics) on this same measure.
The patient was a Jehovah's Witness and refused transfusion; she was started on solumedrol for a diagnosis of autoimmune hemolytic anemia and immune-mediated thrombocytopenia.
375 parenterally every 6 hours; solumedrol was added, given her history of asthma.
Solumedrol use in the acute types of MS has also shown some positive results.
All patients received a standard NIH (National Institutes of Health) induction protocol, which included pulse solumedrol and monthly intravenous cyclophosphamide for 6 months.
As shown in Figure 9, the combination of monthly pulse solumedrol in conjunction with intravenous cyclophosphamide led to improved renal survival at 10 years.
Patient was given 100 mg po qd of cyclophosphamide and 60 mg IV qd of solumedrol and etanercept 25 mg subcutaneously for two weeks.