methylprednisolone(redirected from Solumedrol)
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methylprednisolone/meth·yl·pred·nis·o·lone/ (-pred-nis´ah-lōn) a synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant; also used as m. acetate and m. sodium succinate.
A glucocorticoid used therapeutically primarily as an anti-inflammatory agent.
indications It is prescribed as an antiinflammatory drug and as an immunosuppressant to treat autoimmune disease, cancer, and other disease involving cells of the immune system. It is also administered to suppress graft-versus-host disease after bone marrow transplantation.
contraindications Fungal infections or known hypersensitivity to this drug prohibits its systemic use. Viral or fungal infections of the skin, impaired circulation, or known hypersensitivity to this drug prohibits its topical use.
adverse effects Among the more serious adverse effects of the systemic administration of the drug are upper GI bleeding and endocrine, neurological, fluid, and electrolyte disturbances. Skin reactions may result from topical administration of this drug.
methylprednisoloneA CORTICOSTEROID drug used in a wide range of conditions to control severe inflammation, treat allergies and replace stroid deficiencies. It is commonly used in depot form for long-term action. Brand names are Medrone, Depo-Medrone and Solu-Medrone.
a glucocorticoid with anti-inflammatory action similar to that of prednisolone. The acetate is often prepared in long-acting forms while the water-soluble, rapid-acting succinate is suitable for intravenous administration and is used in the treatment of shock.
a long-acting glucocorticoid, used in the treatment of dermatoses and allergic conditions.