methylprednisolone

(redirected from Solumedrol)
Also found in: Dictionary.

methylprednisolone

 [meth″il-pred-nis´o-lōn]
a synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant; also used as m. acetate and m. sodium succinate.

methylprednisolone

/meth·yl·pred·nis·o·lone/ (-pred-nis´ah-lōn) a synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant; also used as m. acetate and m. sodium succinate.

methylprednisolone

(mĕth′əl-prĕd-nĭs′ə-lōn′)
n.
A glucocorticoid used therapeutically primarily as an anti-inflammatory agent.

methylPREDNISolone

[-prednis′əlōn]
a glucocorticoid.
indications It is prescribed as an antiinflammatory drug and as an immunosuppressant to treat autoimmune disease, cancer, and other disease involving cells of the immune system. It is also administered to suppress graft-versus-host disease after bone marrow transplantation.
contraindications Fungal infections or known hypersensitivity to this drug prohibits its systemic use. Viral or fungal infections of the skin, impaired circulation, or known hypersensitivity to this drug prohibits its topical use.
adverse effects Among the more serious adverse effects of the systemic administration of the drug are upper GI bleeding and endocrine, neurological, fluid, and electrolyte disturbances. Skin reactions may result from topical administration of this drug.

methylprednisolone

A CORTICOSTEROID drug used in a wide range of conditions to control severe inflammation, treat allergies and replace stroid deficiencies. It is commonly used in depot form for long-term action. Brand names are Medrone, Depo-Medrone and Solu-Medrone.

methylprednisolone

a glucocorticoid with anti-inflammatory action similar to that of prednisolone. The acetate is often prepared in long-acting forms while the water-soluble, rapid-acting succinate is suitable for intravenous administration and is used in the treatment of shock.

methylprednisolone-21-dimethylaminoacetate
a long-acting glucocorticoid, used in the treatment of dermatoses and allergic conditions.
References in periodicals archive ?
10 Our patient received injection Solumedrol for early rejection and then was converted to mycophenolate mofetil (potent antiproliferative agent) very early after transplant.
You administer solumedrol intravenously 1 g/d for 3 days, then change to prednisone orally 1 mg/kg/d.
When a decision was made to start corticosteroids, they were initially administered intravenous solumedrol 2 mg/kg per day.
Three days into her hospital course, the patient began to show slow clinical improvement on a medical regimen that included continuous nebulized ventolin treatments, intravenous solumedrol, ipratroprium bromide nebulized treatments, and a continuous terbutaline infusion, which was started on the second hospital day.
So we waited for the nurse, JoAnn Della Valle, to come to our apartment with a week's worth of SoluMedrol and IV injection supplies for a week.
Corticosteroids, such as prednisone, cortisone, solumedrol, and hydrocortisone, are used to treat many rheumatic conditions because they decrease inflammation and suppress the immune system.
Clinical data and the opinions of interviewed thought leaders indicate that Janssen Biotech/Merck/Mitsubishi Tanabe's Remicade, the sales-leading agent in the ulcerative colitis market, offers comparable efficacy in inducing remission compared with oral prednisone and intravenous cyclosporine (Novartis's Sandimmune, generics) but is at a disadvantage to intravenous methylprednisolone (Pfizer's SoluMedrol, Sanofi's Urbason, generics) on this same measure.
The patient was a Jehovah's Witness and refused transfusion; she was started on solumedrol for a diagnosis of autoimmune hemolytic anemia and immune-mediated thrombocytopenia.
He was started on pulse solumedrol 1000 mg IV for presumed acute glomerulonephritis.
375 parenterally every 6 hours; solumedrol was added, given her history of asthma.
The treatment for acute allograft rejection can be solumedrol, monoclonal antibodies (OKT3[TM]), or polyclonal antibodies (Atgam[TM], Thymoglobulin[TM]).
Solumedrol use in the acute types of MS has also shown some positive results.