levothyroxine sodium

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levothyroxine sodium (L-thyroxine, T4)

Eltroxin (CA) (UK), Euthyrox (CA), Evotrox (UK), Levo-T, Levolet, Levothroid, Levoxyl, Nu-Thyro (CA), Soloxine, Synthroid, Unithroid

Pharmacologic class: Synthetic thyroxine hormone

Therapeutic class: Thyroid hormone replacement

Pregnancy risk category A

FDA Box Warning

• Drug shouldn't be used alone or with other agents to treat obesity or weight loss. In euthyroid patients, doses within range of daily hormonal requirements are ineffective for weight loss. Larger doses may cause serious or life-threatening toxicity, particularly when given with sympathomimetic amines (such as those used for anorectic effects).


Synthetic form of thyroxine that replaces endogenous thyroxine, increasing thyroid hormone levels. Thyroid hormones help regulate cell growth and differentiation and increase metabolism of lipids, protein, and carbohydrates.


Powder for injection: 200 mcg/vial in 6- and 10-ml vials, 500 mcg/vial in 6- and 10-ml vials

Tablets: 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, 300 mcg

Indications and dosages

Hypothyroidism; treatment or prevention of euthyroid goiter

Adults: For healthy adults younger than age 50 and those over age 50 who have recently been treated or undergone short-term therapy, start at full replacement dosage of 1.7 mcg/kg P.O. daily, given 30 minutes to 1 hour before breakfast. For patients older than age 50 or younger than age 50 with heart disease, 25 to 50 mcg P.O. daily, increased q 4 to 6 weeks. In severe hypothyroidism, initial dosage is 12.5 to 25 mcg P.O. daily, adjusted by 25 mcg daily q 2 to 4 weeks. For patients who can't tolerate oral doses, adjust I.M. or I.V. dosage to roughly half of oral dosage.

Congenital hypothyroidism

Children older than age 12 who have completed puberty and growth: 1.7 mcg/kg P.O. daily

Children older than age 12 who have not completed puberty and growth: Up to 150 mcg or 2 to 3 mcg/kg P.O. daily

Children ages 6 to 12: 4 to 5 mcg/kg P.O. daily

Children ages 1 to 5: 5 to 6 mcg/kg P.O. daily

Infants ages 6 to 12 months: 6 to 8 mcg/kg P.O. daily

levothyroxine sodium

a thyroid hormone. Also called l -thyroxine.
indication It is prescribed in the treatment of hypothyroidism.
contraindications Recent myocardial infarction or known hypersensitivity to this drug prohibits its use.
adverse effects The most serious adverse effects are angina, tachycardia, arrhythmias, and tremors.

levothyroxine sodium

(lē″vō-thī-rok′sēn″, sĕn) [ levo- + thyroxine],


The sodium salt of the natural isomer of thyroxine used to treat thyroid deficiency. A typical dosage used to treat hypothyroidism is1.6 mcg/kg/day given orally.

levothyroxine sodium (lē´vōthīrak´sēn),

n brand names: Levo-T, Synthroid;
drug class: thyroid hormone;
action: increases metabolic rate, with increase in cardiac output, O2 consumption, body temperature, blood volume, growth/development at cellular level;
uses: hypothroidism, myxedema coma, thyroid hormone replacement, cretinism.
References in periodicals archive ?
In these cases, treatment typically involves replacing the lacking hormone, traditionally with a synthetic thyroid medication such as levothyroxine, commonly sold under the brand name Soloxine, or more recently, ThyroKare.
During more than 30 years of practice, I have found that most dogs require cortisone/cortisol replacement along with a T4 medication such as Soloxine.
However, the major difference between the cases is that Past Experience was prescribed a drug licenced for animal use, Soloxine, albeit one which fell foul of the NGRC rules.
Q MY ten-year-old Boxer has been prescribed Soloxine tablets to help with hair loss on his flanks.
Tonight's BBC1 Watchdog programme found the animal drug Soloxine costs pounds 101.
As a result, he'll need to be on the prescription drug Soloxine for the rest of his life.
Soloxine (levothyroxine sodium) is the most commonly prescribed medication for dogs with hypothyroidism.
At our next visit, I'll recheck Angel's skin and ears and start her on Soloxine, a thyroid medication.
He further stated that because of the undisclosed ingredients, he can't guarantee there will not be negative interactions with the two medications Teddy must take, soloxine for thyroid and Enalapril for his kidneys.
Soloxine holds an estimated 41% share in the canine thyroid hormone replacement market, according to Market Dynamics.
3 million, Tapazole increing Soloxine and Tussigon were up approximately 21 percent to $2.
Sales of Veterinarian products, including Soloxine and Tussigon were relatively flat at $2.