To address this issue, a team of researchers including Di Lorenzo and former graduate student Michael Weiss aimed to detail the effects of obesity on responses to taste stimuli in the nucleus tractus solitarius
, a part of the brain involved with taste processing.
Vagal afferents from the stretch receptors of the lungs are connected with the nucleus tractus solitarius
from which fibers ascend to the limbic areas, thalamus, and anterior cortical areas.
Extended secondhand tobacco smoke exposure induces plasticity in nucleus tractus solitarius
second-order lung afferent neurons in young guinea pigs.
Descending analgesic pathways are activated through nucleus tractus solitarius
by increased vagal stimulation.
Pathogenesis of cognitive dysfunction in patients with obstructive sleep apnea: A hypothesis with emphasis on the nucleus tractus solitarius
. Sleep Disord 2012;2012:251096.
nucleus tractus solitarius
, area postrema), which are responsible for the co-ordination of the efferent limb of the vomiting reflex.
Synaptic failure in the nucleus solitarius
indeed can occur with metabolic or hypoxic/ischemic insults, followed by recovery of those neurons that were rendered nonfunctional for a transitory period without neuronal loss.
These studies demonstrated that GDNF-family receptor a-like (GFRAL) served as a receptor of GDF15 signalling in the hindbrain (i.e., area postrema and nucleus tractus solitarius
) which was required for the metabolic effects of GDF15 [9-11].
 contend in a meta-analysis that dynamic connections between the amygdala and medial prefrontal cortex, which evaluate threat and safety, help regulate HRV through their connections with the nucleus tractus solitarius
Other pharmacologic approaches to pain management include utilizing the antidepressant class such as amitriptyline and nortriptyline or the newer amine reuptake inhibitors such as the SNRI duloxetine, which exert their effects through a multiplicity of mechanisms of action [14, 15] including descending inhibition via the nucleus tractus solitarius