Surveillance Counterpoint: Japan.
In addition, Halaven has been designated as an orphan drug for soft-tissue sarcoma
in the United States and Japan.
Dermatofibrosarcoma was the second most prevalent soft-tissue sarcoma
(56 patients; 18.
The trial is evaluating Zymafos, or palifosfamide, as a treatment for patients with unresectable or metastatic soft-tissue sarcoma
A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma
Today, the list of presumptive service-connected health problems caused by exposure to Agent Orange and other herbicides includes chloracne (a skin disease), Hodgkin's disease, multiple mycloma to (a cancer of the blood cells), non-Hodgkin's lymphoma, porphyria cutanea tarda (a skin disease caused by a defective liver enzyme), respiratory cancers (lung, bronchus, larynx, and trachea), soft-tissue sarcoma
(cancer of the muscles and tendons), acute and subacute peripheral neuropathy (weakening of the nervous system), prostate cancer, chronic lymphocytic leukemia, and adult-onset (Type 2) diabetes.
Dioxins have been linked with Hodgkin disease, non-Hodgkin lymphoma, soft-tissue sarcoma
, and more tentatively with type 2 diabetes mellitus and other conditions.
The seven are: chloracne, Hodgkin's disease, multiple myeloma, non-Hodgkin's lymphoma, porphyria cutanea tarda, respiratory cancers (of the lung, bronchus, larynx and trachea), and soft-tissue sarcoma
At the 38th annual meeting of the American Society of Clinical Oncology in May 2002, the Sloan-Kettering team presented research in which they developed DNA expression profiles that can be used to accurately diagnose nine soft-tissue sarcoma
subtypes, representing approximately 70% of these cancers.
The panel found strong evidence of a statistical association between herbicides or dioxin and soft-tissue sarcoma
, non-Hodgkin's lymphoma, and Hodgkin's disease, three types of cancer.
Maki stated: "Metastatic soft-tissue sarcoma
is a disease for which we have seen few advances in treatment and no U.
Malignant fibrous histiocytoma is the most common soft-tissue sarcoma
of late adult life and accounts for 20% to 30% of all soft-tissue sarcomas