Sofradex

A brand name for eye or ear drops or ointment containing DEXAMETHASONE, FRAMYCETIN and GRAMICIDIN.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

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A general practice study to compare the efficacy and tolerability of spray ('Otomize') versus a standard drop formulation ('Sofradex') in the treatment of patients with otitis externa.

The pH of commonly used topical ear drops in the treatment of otitis externa

A general practice study to compare the efficacy and tolerability of a spray ("Otomize") versus a standard drop formulation ("Sofradex") in the treatment of patients with otitis externa.

Management of the Patient with Otitis Externa

(21) The incidence of tube obstruction in ears treated with dexamethasone 0.05%/framycetin 0.5%/gramicidin 0.005% (Sofradex) was 1.6%, compared with 13.1% for the untreated ears (p = 0.05).

* Uppal et al performed a double-blind in vitro study of 473 blocked grommets to compare the efficacy of 5% sodium bicarbonate, 3% hydrogen peroxide, Sofradex, 0.33% acetic acid, and 0.9% sodium chloride drops.

Prevention and treatment of plugged tympanostomy tubes

Beware of drops that can potentially cause ototoxicity, such as Sofradex, Covomycin-D and other aminoglycoside topical preparations.

An approach to chronic otitis media with effusion--the pros and cons of grommets: grommets or not? This reviews the indications for grommets

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