channel

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Related to Sodium channel: Potassium channel

channel

 [chan´el]
a passage, cut, or groove through which something can pass or flow across a solid structure.
calcium channel (calcium-sodium channel) a slow voltage-gated channel very permeable to calcium ions and slightly permeable to sodium ions, existing in three subtypes designated L, M, and N and located throughout the body; calcium channels are the main cause of action potentials in certain smooth muscles, and the N channels regulate neurotransmitter release.
fast channel a protein channel, such as a sodium channel, that becomes activated relatively quickly; a fast voltage-gated channel has a much lower activation potential than does the slow type. See also slow channel.
ligand-gated channel a protein channel that opens in response to the binding of a molecule (the ligand) to the protein, which causes a conformational change in the protein molecule. See also voltage-gated channel.
potassium channel a slow voltage-gated channel selective for the passage of potassium ions, found on the surface of a wide variety of cells, including nerve, muscle, and secretory cells; its functions include regulation of cell membrane excitability, regulation of repetitive low frequency firing in some neurons, and recovery of the nerve fiber membrane at the end of the action potential.
protein channel a watery pathway through the interstices of a protein molecule by which ions and small molecules can cross a membrane into or out of a cell by diffusion; protein channels play a vital role in depolarization and repolarization of nerve and muscle fibers, and may have physical characteristics such as shape or diameter that particularly attract certain ions.
slow channel a protein channel such as the calcium channel that is slow to become activated; a slow voltage-gated channel has a much higher activation potential than does the fast type. See also fast channel.
sodium channel a type of fast channel selective for the passage of sodium ions. Voltage-gated sodium channels are the main causes of depolarization and repolarization of nerve membranes during the action potential. In cardiac cells they produce phase 0 of the action potential.
voltage-gated channel a protein channel that can be opened or closed in response to changes in the electric potential across a cell membrane. See also ligand-gated channel.
water channel a channel in a cell membrane that permits passage of water molecules; chemical substances such as vasopressin cause the opening of new channels and increase permeability.

chan·nel

(chan'ĕl),
A furrow, gutter, or groovelike passageway.
See also: canal.
[L. canalis]

channel

(chăn′əl)
n.
1. A furrow, tube, or other groovelike passageway through which something flows.
2. An aqueous pathway through a protein molecule in a cell membrane that modulates the electrical potential across the membrane by controlling the passage of small inorganic ions into and out of the cell.
Drug slang A regional street term for a vein into which a drug is injected
Paranormal See Channeler, Energy channel
Physiology A multiprotein transmembrane complex—ionophore—with an amphipathic pore, which is hydrophobic on either side of the membrane and hydrophilic inside

channel 

A concept relating to the evidence that information about a particular feature of an image is transmitted and processed in the visual pathway approximately independently of information about other domains. The evidence was obtained from various experiments: matching, threshold elevation, after-effect, etc. Examples: the three channels of colour vision theory; the spatial frequency channels. See waterfall after-effect.

chan·nel

(chan'ĕl)
A furrow, gutter, or groovelike passageway.
[L. canalis]
References in periodicals archive ?
Maresin1 stimulates alveolar fluid clearance through the alveolar epithelial sodium channel Na, K-ATPase via the ALX/PI3K/Nedd4-2 pathway.
Both cannabis and cocaine have been associated with BrP [12-14], possibly due to their activities on the cardiac voltage-gated sodium channel [14, 15].
Protein alignment and paralogue annotation analyses showed that arginine residue at 838 position of SCN11A is highly conserved among various species and also between different subunits of voltage-gated sodium channels (Fig.
Voltage-gated sodium channels (VGSCs) play an important role in action potential initiation and propagation in excitable cells, including sensory neurons in the TG and DRG, because they are responsible for the initial depolarization of the membrane.
12-lead ECG of sodium channel blocker toxicity before and after administration of sodium bicarbonate is presented in Figures 2(a) and 2(b).
Gizewska et al., "Novel mutations in epithelial sodium channel (ENaC) subunit genes and phenotypic expression of multisystem pseudohypoaldosteronism," Clinical Endocrinology, vol.
Huang et al., "Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure," Circulation, vol.
Christmann et al., "Characterization of the epithelial sodium channel S-subunit in human nasal epithelium," American Journal of Respiratory Cell and Molecular Biology, vol.
GPD1L has a functional link with the cardiac sodium channel Nav 1.5 [7], which is encoded for by the SCN5A gene.
Rossier, "Cell-specific expression of epithelial sodium channel a, [beta]UPSILON] subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry," The Journal of Cell Biology, vol.
(7) Human genes: SLC34A3, solute carrier family 34 (sodium phosphate), member 3; SCNN1B, sodium channel, non-voltage-gated 1, f subunit; SCNN1G, sodium channel, non-voltage-gated 1, y subunit.
* Mechanism of action- works on slow sodium channels

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