snRNP


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LSM2

A gene on chromosome 6p21.3 that encodes a ribonucleoprotein which binds specifically to the 3'-terminal U-tract of U6 snRNA, possibly involved in pre-mRNA splicing.

snRNP

abbrev. SMALL NUCLEAR RIBONUCLEOPROTEIN.
References in periodicals archive ?
For instance, splicing factor Sf3b1, a component of U2 snRNPS involved in both constitutive and alternative splicing, is dysregulated in human and mouse models of pathological cardiac hypertrophy [30].
Further, the domains of the oligonucleotide are independent so transcript binding and U1 snRNP binding can be independently optimized and adapted to a wide array of genes associated with disease.
Mouse Tudor Repeat-1 (MTR-1) is a novel component of chromatoid bodies/nuages in male germ cells and forms a complex with snRNPs. Mech.
A calibration curve was constructed by use of plasmids that contained parts of the mtDNA and human nDNA (snRNP U1A; accession numbers HUMMTCG and AC020945, respectively), the concentration of which was determined by the [A.sub.260]/[A.sub.280] ratio.
Wolfson-Reichlin et al., "Murine and human antibodies to native DNA that cross-react with the A and D SnRNP polypeptides cause direct injury of cultured kidney cells," Journal of Immunology, vol.
EIciRNAs are also abundant in nucleus, such as circEIF3J and circPAIP2, and can bind to U1 snRNP (small nuclear ribonucleoproteins) in nucleus to form EIciRNA-U1 snRNP complexes.
The spliceosome is a massive ribonucleoprotein complex comprising some small "U"s nuclear RNAs (snRNAs) plus different specific proteins, these complexes being referred to as small nuclear ribonucleoproteins (snRNPs or SNURPs).
[5] showed that the symmetrical dimethylation of arginines on coilin supports the formation of CBs, positive on survival motor neuron (SMN) proteins and small nuclear ribonucleoproteins (snRNPs).
The snRNPs ([U.sub.1]-RNP/Sm) are involved in the splicing of precursor messenger RNA.