smooth muscle

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smooth mus·cle

one of the involuntary muscle fibers of the internal organs, blood vessels, and other body structures not under direct control of the will; contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei and a length of 20-200 mcm, or even longer in the pregnant uterus; although transverse striations are lacking, both thick and thin myofibrils occur; smooth muscle fibers are bound together into sheets or bundles by reticular fibers, and frequently elastic fiber nets are also abundant.
See also: involuntary muscles.

smooth muscle

n.
Muscle tissue that contracts without conscious control, having the form of thin layers or sheets made up of spindle-shaped, unstriated cells with single nuclei and found in the walls of the internal organs, such as the stomach, intestine, bladder, and blood vessels, excluding the heart.

smooth muscle

Etymology: AS, smoth
one of three kinds of muscle, composed of elongated, spindle-shaped cells in muscles not under voluntary control, such as the smooth muscle of the intestines, stomach, and other viscera. The nucleated cells of smooth muscle are arranged parallel to one another and to the long axis of the muscle they form. Smooth muscle fibers are shorter than striated muscle fibers, have only one nucleus per fiber, and are smooth in appearance. Biofeedback devices may help many people gain partial control of contractions of involuntary smooth muscles. Also called involuntary muscle, unstriated muscle. Compare cardiac muscle, striated muscle .
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Smooth muscle

smooth mus·cle

(smūdh mŭs'ĕl)
One of the muscle fibers of the internal organs, blood vessels, hair follicles; contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei and a length from 20-200 mcm, or even longer in the pregnant uterus; although transverse striations are lacking, both thick and thin myofibrils occur; such fibers are bound together into sheets or bundles by reticular fibers, and frequently elastic fiber nets are also abundant.
See also: involuntary muscles

smooth muscle

The unstriped involuntary muscle occurring in the walls of blood vessels, the intestines and the bladder, and controlled by the AUTONOMIC NERVOUS SYSTEM and by HORMONES.

smooth muscle

see INVOLUNTARY MUSCLE.
Figure 1: Muscles of the back.
Figure 2: Muscles of the abdominal wall. Superficial layer shown on the right side of the body, deeper layer on the left.
Figure 3: Muscles of the shoulder girdle and upper limb.
Figure 4: Muscles of the shoulder girdle and upper limb.
Figure 5: Muscles of the lower limb. Left leg from the front.
Figure 6: Muscles of the lower limb. Left leg from the back.
Figure 7: Structure of skeletal muscle at progressively higher magnification, from whole muscle to contractile proteins (A-D, F). E represents the 'sliding filaments' diagrammatically.

muscle

contractile soft tissue, responsible for all significant active movements and force-generations in an animal body. Divisible into three classes: (1) skeletal or voluntary muscle the class of muscle acting, in almost all body locations, to move one bone relative to another, the more superficial skeletal muscles being visible under the skin in all but the most obese subjects; (2) cardiac muscle the type unique to the heart; (3) smooth muscle composing the actively adjustable components of the walls of blood vessels and of the gastrointestinal, respiratory, urinary and reproductive tracts. Skeletal and cardiac are the striated muscles; cardiac and smooth share the property of being involuntary. See also muscle fibres, muscle fibre types, myofibrils; Figure 1, Figure 2, Figure 3, Figure 4, Figure 5, Figure 6, Figure 7.

smooth mus·cle

(smūdh mŭs'ĕl)
One of the muscle fibers of the internal organs, blood vessels, hair follicles.

muscle

an organ composed of bundles of fibers that has the power to contract and hence to produce movement. Muscles are responsible for locomotion and help support the body, generate heat and perform a number of other functions. They are of two varieties: striated (or striped, voluntary or skeletal), which makes up most of the meat of a carcass, and smooth (unstriated), which includes all the involuntary muscle of the viscera, heart and blood vessels.
Skeletal muscle fibers range in length from a few millimeters to many centimeters. They also vary in color from white to deep red. Each muscle fiber receives its own nerve impulses, which trigger fine and varied motions. At the signal of an impulse traveling down the nerve, the muscle fiber changes chemical energy into mechanical energy, and the result is muscle contraction. At least two major types of muscle fiber have been identified by histochemical techniques: type I (red) fibers, which have a slow contraction; and type II (white) fibers, which have a fast contraction.
Some muscles are attached to bones by tendons. Others are attached to other muscles, and to skin, producing, for example, the skin twitch, the eye blink and hair erection. Parts of the walls of hollow internal organs, such as the heart, stomach and intestines and also blood vessels, are composed of muscles. See also muscular. For a complete list of named muscles see Table 13.

agonistic muscle
prime mover; a muscle opposed in action by another muscle, called the antagonist.
antagonistic muscle
one that counteracts the action of another muscle (the agonist).
appendicular muscle
one of the muscles of a limb.
arrector pili muscle
small, smooth muscle attached to the bulb of the hair which causes erection of the hair and compression of the attending sebaceous gland when it contracts.
arterial muscle
part of the tunica media; smooth muscle fibers arranged in a circular pattern around the lumen.
articular muscle
one that has one end attached to the capsule of a joint.
axial muscle
1. muscles derived from the somites in the embryo.
2. the muscles around the vertebral column.
muscle biopsy
sample of living muscle obtained by excision or punch.
cardiac muscle
striated involuntary muscle with branched fibers and containing modified fibers which act as cardiac conducting cells.
congenital muscle defects
may be environmental, e.g. nutritional muscular dystrophy, or inherited, e.g. splayleg of piglets.
congenital type II muscle fiber hypertrophy
occurs in the hip joint musculature in German shepherd dogs but there is no detectable abnormality of gait.
cutaneous muscle
striated muscle that inserts into the skin.
double muscle
see myofiber hyperplasia.
esophageal muscle
the tunica muscularis of the esophagus in most domestic animals is mostly striated; in pigs, horses and cats there are small segments of smooth muscle; in birds the entire tunic is smooth muscle.
extraocular m's
the six or seven voluntary muscles that move the eyeball: dorsal, ventral, medial and lateral recti, dorsal and ventral oblique, and retractor bulbi muscles.
extrinsic muscle
one that originates in another part than that of its insertion, e.g. those originating outside the eye, which move the eyeball.
fast-twitch skeletal muscle
two of the three types of skeletal muscle are pale in color and fast-twitch—type IIa (fast-twitch oxidative-glycolytic), type IIb (fast-twitch glycolytic). Type IIa fibers are fatigue-resistant, type IIb fatigue easily.
muscle fiber
see muscle (above).
fixation m's, fixator m's
accessory muscles that serve to steady a part.
hamstring m's
the biceps, semimembranosus and semitendinosus muscles. See also hamstring.
intraocular m's
the intrinsic muscles of the eyeball.
intrinsic muscle
one whose origin and insertion are both in the same part or organ, such as those entirely within the eye.
involuntary muscle
see smooth muscle (below).
iridial muscle
layers of circular (sphincter) and radial (dilator) muscles. See also iris.
jaw muscle
see Table 13.1H muscles of mastication.
laryngeal muscle
see Table 13.1E muscles of the larynx.
limb muscle
see Table 13.3, 13.4 muscles of the fore- and hindlimbs.
masseter muscle
the principal muscle of mastication. See also Table 13.1H.
mylohyoid muscle
see Table 13.1D muscles of the hyoid apparatus.
muscle neoplasms
of striated muscle—rhabdomyoma, rhabdomyosarcoma; of plain muscle—leiomyoma, leiomyosarcoma.
muscle nonstriated
see smooth muscle (below).
orbicular muscle
one that encircles a body opening, e.g. the eye or mouth.
muscle-paralyzing drugs
drugs which produce neuromuscular blockade, used as muscle relaxants during surgical procedures. Include d-tubocurarine, alcuronium chloride, pancuronium, vecuronium, atracurium besylate, succinylcholine.
red muscle
type 1 fibers predominate with slow contraction cycles and aerobic metabolism.
muscle rupture
the muscle may have torn away from its insertion, in which case the tendon will be slack, or it may be a complete or partial separation of the belly of the muscle, when the muscle will be swollen and hard. Structural and conformational changes may result, e.g. in rupture of the gastrocnemius muscle, and the hernias caused by rupture of the ventral abdominal muscles or the diaphragm.
skeletal m's
striated muscles that are attached to bones and typically cross at least one joint. Called also voluntary or striated muscles.
slow-twitch skeletal muscle
type 1 skeletal muscle fibers are bright red and contain large amounts of myoglobin; not easily fatigued.
smooth muscle
plain or involuntary muscle which powers the internal organs and is controlled by the autonomic nervous system; slow contracting cycles and fatigue resistant. Two types listed, visceral and vascular.
sphincter muscle
a ringlike muscle that closes a natural orifice; called also sphincter.
muscle spindle
sensory end-organ attached to the perimysial connective tissue of the muscle.
muscle strain
soreness and stiffness in a muscle due to overexertion or contusion, especially in muscles that have not been conditioned for hard use; some of the muscle fibers may actually tear.
striated muscle
see skeletal muscles (above).
synergic m's
those that assist one another in action.
temporal muscle
a significant muscle of mastication. See also Table 13.1H.
muscle-tendon junction
the union between connective tissue investing muscles and anchoring connective tissue.
type I muscle fiber
see slow-twitch skeletal muscle (above).
type II muscle fiber
see fast-twitch skeletal muscle (above).
type II muscle fiber deficiency
a relative deficiency of type II muscle fibers, with a predominance of type I fibers. An inherited defect in Labrador retrievers. Clinical signs include stunted growth, and muscle weakness and abnormal gait, which subside with rest, from an early age.
voluntary muscle
see skeletal muscle (above).
white muscle
consist of type II fibers; fast contraction fibers and aerobic metabolism are characteristic.
yoked m's
those that normally act simultaneously and equally, as in moving the eyes.
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25 [eth]-M) significantly hyperpolarized the resting membrane potential for human colonic circular smooth muscle cells by 2.
Matrigel-coated transwell experiments indicated that nicotine treatment and PKC activation worked synergistically to enhance invasiveness in the primary human vascular smooth muscle cells.
PASMCs were identified as smooth muscle cells by positive staining with mouse anti-[alpha]-actin antibody and FITC-labeled goat anti-mouse antibody (Figure 1).
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Researchers have known about several signals that can stop smooth muscle cells from dividing and enable them to contract, but little is known about how this cascade of interactions works.
In addition, the smooth muscle cells isolated from the bone marrow are mesenchymal cells, that is, stem cells that can differentiate into several cell types.
Thomas has revealed the results of a new study published online in the Journal of Vascular Research, which links a vitamin K-dependent protein called matrix GLA protein (MGP) to increased mineralization of the smooth muscle cells in the vein wall, which may contribute to the development of varicose veins.
The present study was thus aimed to investigate the effect of PAF on airway smooth muscle cells (ASMC) proliferation and to evaluate the potential role of NF-[kappa]B in this regulation.
One possibility is that arsenic may alter the normal vasomotor tone of blood vessels, which rises from contractility of vascular smooth muscle cells.
The research team examined the effect that the anti-cancer drug Trichostatin A - better known as TSA - had on the levels of receptors on human smooth muscle cells of the womb, or uterus, that are affected by the pregnancy hormone hCG (human chorionic gonadotrophin).

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