smallpox vaccine

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small·pox vac·cine

vaccine of live vaccinia virus suspensions prepared from cutaneous vaccinial lesions of calves (calf lymph) or chick embryo origin; not currently used because of the worldwide elimination of smallpox.

smallpox vaccine

a vaccine prepared from dried smallpox virus. It is currently indicated only for laboratory workers and certain military personnel who could be exposed to pox viruses, but this recommendation could change with bioterrorism concerns.

small·pox vac·cine

(smawlpoks vak-sēn)
Vaccine of live vaccinia virus suspensions prepared from cutaneous vaccinial lesions of calves (calf lymph) or chick embryo origin; not currently used because of the worldwide elimination of smallpox.

smallpox vaccine

A vaccine used to provide immunity against smallpox. The vaccine is made from live vaccinia virus (not from the smallpox virus). Similarities between the two viruses make the vaccine about 95% effective in preventing smallpox in those exposed to the virus. Smallpox vaccine was not used for many years because smallpox had been eradicated worldwide. However, concerns over the use of smallpox as a biological weapon have resulted in vaccination of persons at high risk, e.g., public health workers, health care response teams, members of the armed services. The general public is not being vaccinated. The CDC recommends that persons who could be exposed to the monkeypox virus should also be vaccinated against smallpox.
See also: vaccine
References in periodicals archive ?
Emergents VIGIV is the only FDA-licensed treatment for complications due to smallpox vaccination, said Adam Havey, executive vice president and president biodefense division of Emergent BioSolutions.
After the National Smallpox Vaccination Program ended in October 2003, experts at the Centers for Disease Control and Prevention (CDC; Atlanta, GA, USA) and members of the Advisory Committee on Immunization Practices (ACIP) met to determine future steps for response planning.
The vaccinee was identified as a civilian who had received his first smallpox vaccine in June 2012 under the Department of Defense smallpox vaccination program.
Less than one decade after Boylan summoned the specter of ending childhood smallpox vaccination as the ultimate example of dangerous and unscientific absurdity, the United States Public Health Service issued its 1971 recommendation that "the practice of routine smallpox vaccination is no longer indicated in this country" (2).
The five, attenuated, tissue-cultured LC16m8 vaccine proved to be immunogenic in adults who had never received any smallpox vaccination, and it also produced an adequate booster response in those who had been vaccinated previously.
Summary A single, indeterminate leprosy lesion localised exclusively to a smallpox vaccination scar in a 32-year old Indian male is reported.
While lingering in Calcutta, Uncle Gates receives a smallpox vaccination on the inside of his forearm.
2002); however, smallpox was eradicated from Taiwan in 1955 (Center for Disease Control, Taiwan 2004a, 2004b), and the routine smallpox vaccination program in Taiwan ended in 1979 after the disease was eradicated worldwide following the WHO campaign (BiotechEast 2003; Center for Disease Control, Taiwan 2004a, 2004b; Lee 2003).
Then, given the national and international attention smallpox has received as a likely means of attack, the article presents a thorough discussion of the disease, the historical and current risks of smallpox and smallpox vaccination, and the significance of effective prevention and treatment strategies.
1799: Edward Jenner introduced the smallpox vaccination.