[5] Nonstandard abbreviations: SLE, systemic lupus erythematosus; ANA, antinuclear antibodies; IIT, indirect immunofluorescence test; NALIA, nanodot array luminometric immunoassay; snRNP,
small nuclear ribonucleoprotein; HRP, horseradish peroxidase; PBS, phosphate-buffered saline; CCD, charge-coupled device.
Finally, DDX46 encodes a member of the DEAD box protein family that has putative helicase activity and is involved in pre-mRNA splicing as part of the 17S U2
small nuclear ribonucleoprotein complex.
Small nuclear ribonucleoprotein U1 (U1snRNP), topoisomerase I (Scl-70), and Smith antigen (Sm) were bacterial recombinant proteins purchased from DiaRect AG.
[5] showed that the symmetrical dimethylation of arginines on coilin supports the formation of CBs, positive on survival motor neuron (SMN) proteins and
small nuclear ribonucleoproteins (snRNPs).