Type II lesions present as a cyst, sinus, fistula, or any combination and are of ectodermal and mesodermal origin, containing either skin appendages
or cartilage [4, 5].
Lipofibromas contain fat cells, but no skin appendages
, in the dermis.
Epidermoid cysts are rare, benign developmental cysts, arising from ectodermal tissue lined by epidermis without skin appendages
.1,2 Their incidence in the head and neck region ranges from 1.6% to 6.9% and 1.6% in the oral cavity.
Pathological examination showed a benign cyst with lining of squamous cell epithelium and associated skin appendages
as it is typical for dermoid cysts.
In humans, problems with wound healing can manifest themselves as delayed wound healing (e.g., in diabetes or radiation exposure), excessive healing (e.g., hypertrophic or keloid scars), or a lack of skin appendages
(e.g., hair follicles or sweat glands) .
The absorption of any kind of material there can be considered two general pathways: through the stratum corneum and the underlying layers or along the skin appendages
. Generally, the stratum corneum is assumed to be the main barrier for absorption, through the corneocytes or along the intercellular spaces along the lipid matrix, the latter most suited for penetration, offering channel-like structures providing higher diffusivity although the pathway is much longer (Schneider et al., 2009).
In our study the ectodermal elements consisted of squamous epithelium 95.2% skin appendages
88.1% keratin material 57.1% nervous tissue 33.3% nerve fibers 11.9% choroid epithelium 4.8% transitional epithelium 4.8% and uveal tissue 2.4%.