muscle relaxant

(redirected from Skeletal muscle relaxant)
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relaxant

 [re-lak´sant]
1. causing relaxation.
2. an agent that causes relaxation.
muscle relaxant an agent that specifically aids in reducing muscle tension.

mus·cle re·lax·ant

a drug with the capacity to reduce muscle tone; may be either a peripherally acting muscle relaxant such as curare and act to produce blockade at the neuromuscular junction (and thus useful in surgery), or act as a centrally acting muscle relaxant exerting its effects within the brain and spinal cord to diminish muscle tone (and thus useful in muscle spasm or spasticity).

muscle relaxant

an agent that reduces the contractility of muscle fibers. Curare derivatives and succinylcholine compete with acetylcholine and block neural transmission at the myoneural junction. These drugs are used during anesthesia, in the management of patients undergoing mechanical ventilation, and in shock therapy, to reduce muscle contractions in pharmacologically or electrically induced seizures. Several drugs that relieve muscle spasms act at various levels in the central nervous system: baclofen inhibits reflexes at the spinal level; cyclobenzaprine acts primarily in the brainstem; and the benzodiazepines reduce muscle tension, chiefly by acting on mechanisms that control muscle tone. Dantrolene acts directly on muscles in reducing contraction and apparently achieves its effect by interfering with the release of calcium from the sarcoplasmic reticulum.

muscle relaxant

Anesthesiology An agent used in anesthesiology to facilitate airway management, control alveolar ventilation, abolish motor reflexes, and provide the muscle relaxation. Depolarizing agents, eg succinylcholine, cause a prolonged depolarization of the motor end plate. Nondepolarizing agents, eg pancuronium, are competitive inhibitors of acetylcholine at the motor end plate See Depolarizing agent, Nondepolarizing agent.

mus·cle re·lax·ant

(mŭsĕl rĕ-laksănt)
Drug able to reduce muscle tone; may be either a peripherally acting muscle relaxant or act centrally acting.

mus·cle re·lax·ant

(mŭsĕl rĕ-laksănt)
Drug with capacity to reduce muscle tone; may be either a peripherally acting muscle relaxant such as curare and act to produce blockade at the neuromuscular junction (and thus useful in surgery), or act as a centrally acting muscle relaxant exerting its effects within the brain and spinal cord to diminish muscle tone (and thus useful in muscle spasm or spasticity).

muscle relaxant

an agent that specifically aids in reducing muscle tone. Most such agents inhibit the transmission of nerve impulses at the somatic neuromuscular junctions. They include tubocurarine, gallamine, pancuronium, succinylcholine and decamethonium bromide.
References in periodicals archive ?
They recommended considering nonsteroidal anti-inflammatory drugs or skeletal muscle relaxants for patients who want medications for acute or subacute low back pain.
NEJM Journal Watch notes in its analysis of the recommendations that within these reviews, there is evidence that skeletal muscle relaxants for acute pain may also be effective.
Among patients with acute nonspecific mechanical LBP, the most frequent pharmacological approach is the admin istration (or self-administration) of paracetamol, nonsteroidal anti-inflammatory drugs (NSAID) and skeletal muscle relaxants.
Chapter 7: Skeletal muscle relaxants and antispasticity drugs for orofacial pain disorders
Symptomatic treatment can be given with anti-inflammatory drugs and skeletal muscle relaxants.
They recommend considering nonsteroidal anti-inflammatory drugs or skeletal muscle relaxants for patients who want medications for acute or subacute low back pain.
The clinical management system reviews medications within certain drug categories that have the potential for abuse, including tranquillizers, skeletal muscle relaxants and anorexients/amphetamines.