In addition, an outbreak of arboviral infections, particularly Sindbis
virus, had been reported in the Johannesburg area coinciding with the travel dates of the patients we report (10).
Louis ensefaliti, Bati Nil Virusu, Bati Equine ensefaliti, Deng virusu, Rift Vadisi Hummasi, Sari Humma, Murray Vadisi ensefaliti, O'Nyong-nyong, Ross River, Chikungunya, Zika, Sindbis
ve filariasis gibi bircok hastaligin bulastirilmasinda onemli rol oynamaktadirlar (1, 7).
Levine, "Autophagy protects against Sindbis
virus infection of the central nervous system," Cell Host & Microbe, vol.
Toward this goal, next-generation encephalitic alphavirus vaccine candidates, including live-attenuated, inactivated, Sindbis
virus-based chimeric, virus replicon particle, virus-like particle, DNA, and virus-vectored vaccines, are all currently at various stages of development [20-22].
virus), respiratory syncytial virus (RSV) and vesicular stomatitis virus (VSV) are examples of enveloped single-stranded RNA-containing viruses.
Several mosquito-borne arboviruses including West Nile virus (WNV) and Sindbis
virus (SINV) were historically reported from both military members and local mosquitoes in the region.
Brown, "Comparison of Sindbis
virus-induced pathology in mosquito and vertebrate cell cultures," Virology, vol.
Ahronowitz said, including measles, chikungunya, West Nile virus, O'nyong-nyong fever, Mayaro virus, Sindbis
virus, Ross river disease, Ebola/Marburg, dengue, and Zika.
A live, nonattenuated vaccine constructed from Eastern equine encephalitis (EEE) virus and Sindbis
virus has demonstrated the ability to protect primates from EEE.
(1) The alphavirus genus includes about 29 species, seven of these viruses can causes joint disorders in humans including CHIKV, O'nyong-nyong (Central Africa), Ross River and Barmah Forest (Australia and the Pacific), Semliki Forest (Africa), Sindbis
(Africa, Asia, Australia and Europe), and Mayaro (South America and the French Guyana).
2012), considerandose una especie versatil en la ocupacion de habitats disponibles en ecosistemas humanos, ornitofilicos, pero adaptable al ambiente antropico, siendo un vector del virus Nilo del occidente (WNV), virus de la encefalitis de San Luis (SLEV), dengue (DENV), virus Sindbis
y virus de la fiebre del Valle Rift (Andreadis et al.
The synthesized Schiff bases were evaluated for activity against several RNA- and DNA-viruses, using the following cell-based-assays: (a) Vero cells infected with parainfluenza-3 virus, reovirus-1, Sindbis
virus, Coxsackie B4 virus, or Punta Toro virus; (b) human embryonic lung (HEL) fibroblasts infected with herpes simplex virus-1 (KOS), herpes simplex virus-2 (G), acyclovir-resistant herpes simplex virus-1 (KOS ACVr TK-), vaccinia virus or vesicular stomatitis virus; (c) human epithelial (HeLa) cells infected with vesicular stomatitis virus, coxsackie B4 virus or respiratory syncytial virus and (d) Madin Darby canine kidney (MDCK) cells infected with influenza virus, subtype A/H1N1, A/H3N2 or B.