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Related to Simmonds' disease: Simmonds syndrome
panhypopituitarism in which cachexia is a prominent feature; it usually follows destruction of the pituitary gland by surgery, infection, injury, or tumor, but may also occur after difficult labor in childbirth. Symptoms, which vary in intensity, are extreme weight loss, debility, pallor, dry yellowish skin, a slow pulse, hypotension, and atrophy of the genitalia and breasts, progressing to premature senility. Treatment is by regular administration of the various hormones whose release is normally dependent on pituitary function. Called also pituitary cachexia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Simmonds' diseaseUnderactivity of the pituitary gland with resultant inadequacy of hormone production by the other endocrine glands. There is lassitude, loss of body hair, loss of sexual interest, abnormally low blood pressure, MYXOEDEMA and intolerance to cold. Panhypopituitarism. Compare SHEEHAN'S SYNDROME. (Morris Simmonds, 1855–1925, Danish-born German pathologist).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005