silibinin

(redirected from Silipide)

silibinin

One of two major constituents of silymarin (silibinins A and B), the main extract of milk thistle (Silybum marianum seeds), which have hepatoprotective effects (e.g., against Amanita phalloides (deathcap mushroom) poisoning) and anti-cancer activity (in animal models) against prostate adenocarcinoma, breast carcinoma cells, cervical carcinoma cells, colon cancer and both small and non-small lung carcinomas. It may also be useful for cirrhosis and type-2 diabetes.
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Protective activity of silipide on liver damage in rodents.
Comparative bioavailability of silipide, a new flavanolignan complex, in rats.
Special formulations of silybin have been developed to enhance the bioavailability of the herbal product; these forms are sold under the names Legalon[R], Silipide and Siliphos.